| Recruiting | A Study Of CS Reducer For Symptomatic Heart Failure With HFpEF And CMD NCT07093528 | Mayo Clinic | — |
| Recruiting | Self-Expanding Coronary Sinus Reducer for Treatment of Symptomatic Coronary Microvascular Dysfunction (CMD) (S NCT06991322 | VahatiCor, Inc. | N/A |
| Recruiting | Assessment of Coronary Microvascular Dysfunction After STEMI Using Continuous Saline Thermodilution NCT06795035 | The Cleveland Clinic | — |
| Recruiting | Improving Coronary Vascular Health in Women NCT06843902 | Massachusetts General Hospital | Phase 2 |
| Enrolling By Invitation | Effects of Immune Checkpoint Inhibitors on Coronary Microvasculature NCT06332131 | Abramson Cancer Center at Penn Medicine | — |
| Recruiting | The Effects of Tirzepatide in People With Overweight/Obesity and Coronary Artery Disease NCT06606821 | Tina Vilsbøll | Phase 4 |
| Not Yet Recruiting | Mechanisms Behind Microvascular Dysfunction in INOCA NCT06529861 | Bispebjerg Hospital | — |
| Recruiting | Insulin Resistance and Coronary Microvascular Dysfunction in Patients with Myocardial Ischemia and Non-obstruc NCT06597851 | Azienda Ospedaliera Universitaria Integrata Verona | N/A |
| Recruiting | Southeastern Europe Microcirculation Registry NCT06393478 | Institute for Cardiovascular Diseases Dedinje | — |
| Recruiting | Study of Microvascular Dysfunction, CFR and Cardioprotective Effect of Early Administration of Esmolol in MI NCT06376630 | National Medical Research Center for Cardiology, Ministry of Health of Russian Federation | N/A |
| Not Yet Recruiting | Impact of Renal Denervation in Patients With Coronary Microvascular Dysfunction: Study Design and Rationale NCT05994729 | Aurelia Hospital | N/A |
| Recruiting | Coronary Flow During Rapid Heart Rates NCT05841199 | Imperial College London | — |
| Active Not Recruiting | Multimodal Epicardial and Endocardial COronary PHYsiological Evaluation in Pathological Situations (PHYCO) NCT06008041 | University Hospital, Brest | — |
| Recruiting | A Study on the Impact of Bivalirudin Usage During PCI for High-risk Plaques on Post-PCI Coronary Microcirculat NCT05984537 | Peking University First Hospital | Phase 4 |
| Recruiting | Coronary Microvascular Dysfunction in Angina Patients With Non-obstructive Coronary Artery Disease (ANOCA-CMD) NCT06503640 | China-Japan Friendship Hospital | — |
| Completed | Vericiguat in Patients With Metabolic Syndrome and Coronary Vascular Dysfunction NCT05711719 | Johns Hopkins University | Phase 2 |
| Unknown | COVID-19 Microvascular Evaluation Trial NCT05841485 | Lithuanian University of Health Sciences | — |
| Enrolling By Invitation | CMR in T2DM: The NSR Cohort NCT05915260 | Slagelse Hospital | — |
| Completed | Super Saturated Oxygen (SSO2) Therapy in Patients With ST-segment Elevation Myocardial Infarction (STEMI) and NCT05790876 | University Hospital, Grenoble | N/A |
| Recruiting | Coronary Microvascular Disease (CMD) Registry NCT05960474 | Medstar Health Research Institute | — |
| Active Not Recruiting | The DISCOVER INOCA Prospective Multi-center Registry NCT05288361 | Yale University | — |
| Completed | Simultaneous Assessment of Coronary Microvascular Dysfunction and Ischemia With Non-obstructed Coronary Arteri NCT05471739 | Istanbul University | — |
| Unknown | Randomized Trial to Examine a Differential Therapeutic Response in Symptomatic Patients With Non-obstructive C NCT05294887 | Charite University, Berlin, Germany | Phase 4 |
| Recruiting | Coronary Microvascular Dysfunction Assessments in Myocardial Infarction With Non-Obstructive Coronary Arteries NCT05272618 | Chonnam National University Hospital | — |
| Completed | MCG as a Noninvasive Diagnostic Strategy for Suspected Coronary Microvascular Dysfunction NCT05150054 | Genetesis Inc. | — |
| Recruiting | Belgian Registry on Coronary Function Testing NCT06089031 | University Hospital, Antwerp | — |
| Completed | A Prospective, Multi-center Clinical Trial for Evaluating the Effectiveness and Safety of Online Coronary Angi NCT05009667 | Ge Junbo | — |
| Completed | Feasibility and Efficacy of Coronary Sinus Narrowing in Patients With Coronary Microvascular Dysfunction NCT04523168 | Amir Lerman | N/A |
| Unknown | Absolute Flow for Ischemia With No Obstructive Coronary Arteries NCT05825339 | Spanish Society of Cardiology | — |
| Unknown | Diagnostic and Prognostic Value of Angiography-derived IMR NCT04825028 | Shanghai Zhongshan Hospital | — |
| Unknown | Distribution and Clinical Implication of CMD in Patients With HFpEF Without Significant CAD NCT04788576 | Samsung Medical Center | — |
| Completed | Microvascular Dysfunction in Adults With Congenital Heart Disease and the Effect of Exercise Training NCT06715137 | University Hospital, Antwerp | N/A |
| Terminated | A Placebo-Controlled Trial of CLBS16 in Subjects With Coronary Microvascular Dysfunction NCT04614467 | Lisata Therapeutics, Inc. | Phase 2 |
| Enrolling By Invitation | The NetherLands Registry of Invasive Coronary Vasomotor Function Testing (NL-CFT) NCT06083155 | Radboud University Medical Center | — |
| Unknown | Microvascular Coronary Resistance and Absolute Coronary FLOW in Patients With Percutaneous Intervention of a C NCT05197361 | Parc de Salut Mar | — |
| Recruiting | Women's Ischemia Syndrome Evaluation (WISE) Pre-HFpEF NCT03876223 | Cedars-Sinai Medical Center | — |
| Completed | COronary Microcirculation and Troponin Elevation in Septic Shock NCT06294730 | Karolinska Institutet | — |
| Completed | Safety and Potential Bioactivity of CLBS16 in Patients With Coronary Microvascular Dysfunction and Without Obs NCT03508609 | Lisata Therapeutics, Inc. | Phase 2 |
| Completed | The Evaluation of Left Ventricular Systolic Function in Different Types of Ischemic Heart Disease NCT04959357 | Peking University Third Hospital | — |
| Completed | Comprehensive Functional Assessments for NOCAD NCT06175572 | Shanghai Zhongshan Hospital | — |
| Completed | Effect of Intact GLP-1 (7-36) and GLP-1 Metabolite (9-36) on Coronary and Peripheral Vascular Function in Adul NCT02333591 | Mette Zander | Phase 4 |
| Completed | Coronary Thermo-dilution Derived Flow-indices in Chronic Coronary Syndrome NCT06306066 | Karolinska Institutet | — |
| Completed | Microcirculation Assessment in Diabetes and Metabolic Syndrome NCT01014949 | S.M. Misericordia Hospital | N/A |