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Active Not RecruitingNCT06008041

Multimodal Epicardial and Endocardial COronary PHYsiological Evaluation in Pathological Situations (PHYCO)

Multimodal Epicardial and Endocardial COronary PHYsiological Evaluation in Pathological Situations

Status
Active Not Recruiting
Phase
Study type
Observational
Enrollment
400 (estimated)
Sponsor
University Hospital, Brest · Academic / Other
Sex
All
Age
18 Years – 100 Years
Healthy volunteers
Not accepted

Summary

When performing coronary angiography in a stable situation, the identification of an intermediate coronary lesion (between 50 and 70%) is common, and requires additional functional evaluation. The gold standard for this evaluation is Fractional Flow Reserve (FFR). FFR is a flow ratio transformed into a pressure ratio by simplification, neglecting some parameters, especially microcirculatory resistance. The aim of this study is to investigate hemodynamic and structural assessment induced in specific conditions, and their repercussion on functional assessment by FFR to implement the diagnostic approach and personalize it for each patient.

Conditions

Timeline

Start date
2023-07-13
Primary completion
2023-07-13
Completion
2027-04-01
First posted
2023-08-23
Last updated
2023-08-28

Locations

1 site across 1 country: France

Source: ClinicalTrials.gov record NCT06008041. Inclusion in this directory is not an endorsement.