| Recruiting | Tolecizumab Plus Chemoimmunotherapy for pMMR/MSS Locally Advanced Colon Adenocarcinoma NCT07468630 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | Phase 2 |
| Not Yet Recruiting | COLON ERDERLY LOW DOSE NCT06840977 | Matteo Clavarezza | — |
| Not Yet Recruiting | Comparison of Laparoscopic and Open Total Mesocolic Excision With Central Vascular Ligation for Right Colon Ca NCT07361016 | Kafrelsheikh University | N/A |
| Not Yet Recruiting | Family Communications After Genetic Testing NCT07143487 | Alliance for Clinical Trials in Oncology | N/A |
| Recruiting | A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Canc NCT06997497 | Merck Sharp & Dohme LLC | Phase 3 |
| Not Yet Recruiting | Current Microsatellite Stability Results in Colon Cancer NCT06971107 | Turkish Society of Colon and Rectal Surgery | — |
| Completed | Survival Outcomes by Tumor-Node Stage and Recurrence Patterns in Colon Cancer After Radical Surgery NCT07167147 | Chang Gung Memorial Hospital | — |
| Recruiting | Evaluation of PreveCol's Efficiency As a Second Line Method for the Early Colorectal Cancer Detection NCT06703632 | ADVANCED MARKER DISCOVERY S.L. | N/A |
| Recruiting | Sentinel Node and Organ-sparing Surgery in Stage I Colon Carcinoma NCT06652672 | Meander Medical Center | N/A |
| Completed | PeLear CCC: Proyecto Latino Contra Cancer Colorrectal NCT06426927 | University of North Carolina, Chapel Hill | N/A |
| Recruiting | HDAC Inhibitor Combination With Chemoimmunotherapy in the Neoadjuvant Treatment of pMMR Locally Advanced Colon NCT06709885 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | Phase 2 |
| Recruiting | Encorafenib + Cetuximab Beyond Progression in Combination With FOLFIRI in Patients With BRAF V600E Mutated Met NCT06640166 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | Phase 2 |
| Completed | Optimization of Adaptive Text Messages for Cancer Survivors (OATS II) NCT05746195 | University of California, San Francisco | N/A |
| Active Not Recruiting | Testing the Use of BRAF-Targeted Therapy After Surgery and Usual Chemotherapy for BRAF-Mutated Colon Cancer NCT05710406 | Alliance for Clinical Trials in Oncology | Phase 2 / Phase 3 |
| Recruiting | Inhalational or Intravenous Anesthesia During Surgery for Patients With Colon Cancer, VIVA Study NCT06017141 | University of Kansas Medical Center | Phase 2 |
| Recruiting | Evaluating Novel Therapies in ctDNA Positive GI Cancers NCT05482516 | Georgetown University | Phase 3 |
| Recruiting | Pilot Study for Colorectal Cancer and Advanced Adenoma Detection With the Mainz Biomed Colorectal Cancer Test NCT06864338 | Mainz Biomed | — |
| Completed | Dynamics of MSI and Genomic Profile of Colorectal Cancer In the Course of Immune Checkpoint Inhibitor Therapy NCT06414304 | OncoAtlas LLC | — |
| Unknown | Role of Immunoscore® in Stage II-III Colorectal Cancer NCT05422547 | D'Or Institute for Research and Education | — |
| Completed | Performance of Artificial Intelligence in Colonoscopy for Right Colon Polyp Detection NCT06216405 | Groupe Hospitalier Diaconesses Croix Saint-Simon | N/A |
| Recruiting | LDLT in Non Resectable Colo-rectal Cancer Liver Metastasis NCT05186116 | Azienda Ospedaliero-Universitaria di Modena | N/A |
| Recruiting | Study of ctDNA Guided Change in Tx for Refractory Minimal Residual Disease in Colon Adenocarcinomas NCT04920032 | University of California, Irvine | Phase 1 |
| Active Not Recruiting | Study of Cabozantinib and Nivolumab in Refractory Metastatic Microsatellite Stable (MSS) Colorectal Cancer NCT04963283 | University of Colorado, Denver | Phase 2 |
| Completed | The Safety and Feasibility of MONOFIX on Fascial Closure of Mid-line Wound After Minimally Invasive Colorectal NCT05872334 | Samsung Medical Center | N/A |
| Unknown | Combined Neoadjuvant Systemic and PIPAC Therapy (NASPIT) for Patients With Colorectal Peritoneal Metastasis El NCT04475159 | Prof. Aviram Nissan | Phase 2 |
| Completed | Validation of Aer-O-Scope Colonoscope System Cecal Intubation NCT03949777 | GI View Ltd. | N/A |
| Active Not Recruiting | Circulating Tumor DNA Testing in Predicting Treatment for Patients With Stage IIA Colon Cancer After Surgery NCT04068103 | NRG Oncology | Phase 2 / Phase 3 |
| Unknown | Acute Effect of modeRate-intensity aerOBIc Exercise on Colon Cancer Cell Growth NCT04057274 | Northumbria University | N/A |
| Completed | Peptide-based Immunization for Colon- and and Pancreas-carcinoma NCT03871790 | CENTOGENE GmbH Rostock | — |
| Completed | M7824 in Patients With Metastatic Colorectal Cancer or With Advanced Solid Tumors With Microsatellite Instabil NCT03436563 | M.D. Anderson Cancer Center | Phase 1 / Phase 2 |
| Completed | Audit of Surgery for Colorectal Cancer NCT04349384 | Institut National d'Oncologie, Morocco | — |
| Completed | Treatment and Outcomes of Stage III Colon Cancer in Patients 80 Years of Age and Older NCT04526314 | Registre des Tumeurs Digestives du Finistère | — |
| Completed | S1613, Trastuzumab and Pertuzumab or Cetuximab and Irinotecan Hydrochloride in Treating Patients With Locally NCT03365882 | SWOG Cancer Research Network | Phase 2 |
| Active Not Recruiting | Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Def NCT02912559 | National Cancer Institute (NCI) | Phase 3 |
| Completed | The Pathogenesis of Chronic Diarrhoea After Treatment for Cancer in Cecum and the Ascending Colon NCT04003181 | University of Aarhus | N/A |
| Completed | Study of the Immune Response in Colon Adenocarcinoma NCT03015038 | Institut National de la Santé Et de la Recherche Médicale, France | — |
| Completed | Oxaliplatin Microdosing Assay in Predicting Exposure and Sensitivity to Oxaliplatin-Based Chemotherapy NCT02569723 | Edward Kim | N/A |
| Completed | Nintedanib and Capecitabine in Treating Patients With Refractory Metastatic Colorectal Cancer NCT02393755 | Roswell Park Cancer Institute | Phase 1 / Phase 2 |
| Completed | Lower or Standard Dose Regorafenib in Treating Patients With Refractory Metastatic Colorectal Cancer NCT02368886 | Academic and Community Cancer Research United | Phase 2 |
| Completed | Whole-Exome Sequencing (WES) of Cancer Patients NCT02127359 | Dana-Farber Cancer Institute | — |
| Active Not Recruiting | Young-Onset Colorectal Cancer NCT02863107 | M.D. Anderson Cancer Center | — |
| Unknown | Molecular Profiling of Colorectal Cancer NCT04863768 | Hellenic Cooperative Oncology Group | — |
| Active Not Recruiting | Oxaliplatin, Leucovorin, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone NCT00217737 | National Cancer Institute (NCI) | Phase 3 |
| Completed | Fluorouracil, Leucovorin, and Oxaliplatin With or Without Bevacizumab in Treating Patients Who Have Undergone NCT00096278 | National Cancer Institute (NCI) | Phase 3 |
| Withdrawn | Pan FGFR Kinase Inhibitor BGJ398 and Combination Chemotherapy in Treating Patients With Untreated Metastatic P NCT02575508 | Roswell Park Cancer Institute | Phase 1 / Phase 2 |