| Not Yet Recruiting | MRI Assessment of Velopharyngeal Anatomy After Modified Furlow-Buccinator Flap in Late Primary Palate Repair NCT07514091 | Cairo University | N/A |
| Not Yet Recruiting | Effects of AlignBabyCleft (ABaCleft) NCT05357092 | Universidad Complutense de Madrid | N/A |
| Not Yet Recruiting | Early Intervention in Infants With Unrepaired Cleft Palate: Language, Palatal Function, and Articulation. NCT07219901 | Old Dominion University | N/A |
| Recruiting | Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery NCT06962306 | Duke University | Phase 4 |
| Not Yet Recruiting | Role of Plasma Rich Growth Factor in Repair Primary Cleft Palate NCT06889181 | Cairo University | N/A |
| Recruiting | Effect of Furlow Palatoplasty With Buccal Myomucosal Flap on the Speech Development NCT06856330 | Fayoum University | — |
| Recruiting | QL vs LAI for Palatoplasty NCT06420336 | Medical University of South Carolina | N/A |
| Not Yet Recruiting | Velopharyngeal Insufficiency Evaluation Post Cleft Palate Repair. Furlow With Buccinator Myomucosal Flap Versu NCT06477679 | Sohag University | N/A |
| Enrolling By Invitation | Book Sharing for Toddlers With Clefts NCT06338319 | Seattle Children's Hospital | N/A |
| Completed | Furlow With Buccinator and Velopharyngeal Function NCT06229587 | Fayoum University | N/A |
| Completed | Repair of Oronasal Fistula Using Interpositional Buccal Pad of Fat as a Free Graft in a Cleft Palate Patient NCT06807450 | Tanta University | N/A |
| Unknown | Etiological Study of Persistent Velopharyngeal Insufficiency in Children With Operated Velopalatine Cleft by A NCT06072495 | Centre Hospitalier Universitaire, Amiens | N/A |
| Completed | Three Dimensional Evaluation of Dento-Skeletal Effects of Leaf Self Expander in Cleft Lip and Palate Patients NCT07384338 | Al-Azhar University | N/A |
| Completed | Comparison of Different Feeding Appliances for Cleft Palate Babies NCT06103162 | Tanta University | N/A |
| Recruiting | Maxillary Nerve Blocks in Children - An MRI Study of the Suprazygomatic Approach NCT05778903 | Oslo University Hospital | N/A |
| Completed | Effect of Collagen Matrix Graft on Palatal Fistula Formation After Cleft Palate Repair NCT05454670 | Lagos State University | N/A |
| Completed | Cleft Palate Technique and Maxillary Growth NCT05405738 | Fayoum University | — |
| Unknown | Comparing the Side-lying Sleep Positioning to Back-lying in Infants With Cleft Palate NCT04478201 | Manchester University NHS Foundation Trust | N/A |
| Completed | LIMA Protocol Towards Palatal Fistula and Maxillary Growth in Cleft Palate NCT07137169 | Indonesia University | N/A |
| Recruiting | A Single Bolus of Dexmedetomidine Versus Normal Saline in Postoperative Agitation NCT04928391 | Assiut University | Phase 3 |
| Recruiting | Nebulized Bupivacaine Analgesia for Cleft Palate Repair NCT04928352 | Assiut University | Phase 3 |
| Completed | Effect of Neck Extension on Intraocular Pressure in Patients Undergoing Palatoplasty NCT04683978 | Asan Medical Center | — |
| Completed | Three-dimensional Cleft Lip and Palate Morphology Prior to One-stage Cleft Repair NCT04616690 | University Hospital, Basel, Switzerland | — |
| Completed | Characteristics of a Maxillofacial Prosthesis Consultation Within Assistance Publique - Hopitaux de Paris NCT04277273 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Optic Nerve Sheath Diameter Measurement in Cleft Palate Repair NCT04718558 | Karadeniz Technical University | — |
| Completed | Assessment of the Influence of Cleft Repair on Microcirculation of the Palate NCT03877666 | University Hospital, Basel, Switzerland | — |
| Recruiting | Neural Network to Calculate Morphology of the Cleft Palate to Reduce Cleft Lip and Palate Treatment Burden. NCT04342234 | University Hospital, Basel, Switzerland | — |
| Completed | Effect of Cleft Palate Repair Using Alveolar Extension Technique on Eruption and Growth NCT05286398 | Mansoura University | N/A |
| Completed | Fistiulation Rate Following Primary Cleft Repair≤ NCT05166408 | Cairo University | N/A |
| Withdrawn | The Use of Fibrin Sealant to Reduce Post Operative Pain in Cleft Palate Surgery NCT02953145 | University of Alberta | Phase 4 |
| Terminated | Exercises for Improving Soft Palate and Eustachian Tube Function in Children With Ear Tubes With or Without Cl NCT03868891 | Noel Jabbour | N/A |
| Completed | Cleft Palate With Intravelar Veloplasty Repair NCT05196555 | Hams Hamed Abdelrahman | N/A |
| Withdrawn | Analgesic Contribution of the Suprazygomatic Maxillary Nerve Block for Cleft Palate Surgery in Children NCT04023825 | Centre Hospitalier Universitaire, Amiens | N/A |
| Unknown | Bone-borne Palatal Expander With Corticotomy for Cleft Palate Patients NCT03837652 | Sarah Ahmed Sameh | N/A |
| Active Not Recruiting | Evaluation of Trigeminal Nerve Blockade NCT03632044 | University of Florida | Phase 4 |
| Withdrawn | Use of Titanium Plate in Rhinoplasty in Patients With Cleft Lip and Palate : Aesthetic and Functional Impact. NCT03572907 | Hospices Civils de Lyon | — |
| Completed | Optic Nerve Sheath Diameter in Patients Undergoing Palatoplasty NCT03585608 | Asan Medical Center | — |
| Active Not Recruiting | Targeting Surgeons' Decision-Making for Cleft Lip Surgery NCT03537976 | Tufts University | N/A |
| Completed | Suprazygomatic Block in Cleft Palate Surgery in Children NCT03412474 | Assiut University | Phase 2 |
| Withdrawn | Dexmedetomidine vs Placebo for Pediatric Cleft Palate Repair NCT02915042 | Baylor College of Medicine | Phase 4 |
| Completed | Characterization of Cleft Lip and Palate Conditions in Guatemala NCT04725370 | Children's Hospital of Philadelphia | — |
| Enrolling By Invitation | Allied Cleft & Craniofacial Quality-Improvement and Research Network (ACCQUIREnet) NCT02702869 | Duke University | — |
| Unknown | Development of the Palate in Bilateral Orofacial Cleft Newborns One Year After Early Neonatal Cheiloplasty NCT03839290 | Charles University, Czech Republic | — |
| Completed | Semi-occluded Vocal Tract Exercise in Velopharyngeal Dysfunction in Patients With Cleft Palate NCT03966482 | Hospital de Clinicas de Porto Alegre | N/A |
| Withdrawn | The Role of Antibiotic Prophylaxis in Cleft Palate and Velopharyngeal Insufficiency Repair NCT02688634 | University of Florida | — |
| Withdrawn | IV Acetaminophen in Children Undergoing Palatoplasty NCT01760330 | Nationwide Children's Hospital | Phase 2 |
| Completed | Botulinum Toxin to Improve Cosmesis of Primary Cleft Lip Repair NCT02247193 | The University of Texas Health Science Center, Houston | Phase 1 / Phase 2 |
| Completed | Improving Outcomes in Cleft Palate Surgery NCT02583100 | Children's Hospital Medical Center, Cincinnati | N/A |
| Completed | Validation of a Production Method of Stem Cell Isolated From the Nasal Cavity for an Innovative Cell Therapy o NCT02900014 | Assistance Publique Hopitaux De Marseille | N/A |
| Completed | Using of Acellular Dermal Matrix in Cleft Palatal Fistula and Compare With Use of Conchal Cartolage NCT03170505 | Isfahan University of Medical Sciences | — |
| Completed | Follow Ups of Parents With Infants With Cleft Lip and Palate NCT02415361 | Oslo University Hospital | N/A |
| Unknown | Improving Informed Consent for Cleft Palate Repair NCT02595307 | IWK Health Centre | N/A |
| Completed | Acid Tranexamic Effectiveness in Reducing the Intraoperative Bleeding in Palatoplasty NCT02422056 | Professor Fernando Figueira Integral Medicine Institute | Phase 4 |
| Completed | Mordified Restoration of Tensor Veli Palatini in Cleft Palate Repair NCT04366674 | Peking Union Medical College Hospital | N/A |
| Completed | Acellular Dermal Matrix in Primary Palatoplasty NCT01867632 | Mirko S. Gilardino | — |
| Completed | Cell Therapy for Craniofacial Bone Defects NCT01616953 | University of Michigan | Phase 1 / Phase 2 |
| Recruiting | Genetics of Reproductive Disorders (Including Kallmann Syndrome) and Cleft Lip and/or Palate NCT01601171 | Centre Hospitalier Universitaire Vaudois | — |
| Completed | Furlow Palatoplasty With Tensor Tenopexy NCT01535131 | University of Pittsburgh | N/A |
| Completed | Efficacy of Oral Versus Intravenous Acetaminophen for Primary Pediatric Cleft Palate Repair NCT01500109 | Loma Linda University | N/A |
| Completed | Does Use of Rigid Fixation After Removing Distraction Osteogenesis Device Reduce the Relapse? NCT02350803 | Shiraz University of Medical Sciences | Phase 2 |
| Completed | Postoperative Complications After Cleft Palate Closure in Patients With Pierre Robin Sequence: Operative Consi NCT02658318 | AZ Sint-Jan AV | — |
| Completed | FaceBase Biorepository NCT01252264 | Jeff Murray | — |
| Completed | Timing of Primary Surgery for Cleft Palate NCT00993551 | Kevin Munro | N/A |
| Completed | Relational Development in Children With Cleft Lips and Palates: Influence of the Waiting Period Prior to the F NCT00993993 | University Hospital, Strasbourg, France | — |
| Completed | Evaluation of Facial Growth in Two Primary Protocols Used in the Surgical Treatment of Unilateral Cleft Lip an NCT02329509 | Professor Fernando Figueira Integral Medicine Institute | N/A |
| Completed | Articulation and Phonology in Children With Unilateral Cleft Lip and Palate NCT00829101 | Region Skane | — |
| Completed | Pilot Study Evaluating Characteristic Closure Patterns of the Normal Velopharyngeal Portal NCT00773994 | University of Pittsburgh | N/A |
| Unknown | An Investigation for the Optimal Timing of a Cleft Palate Repair NCT00779961 | The Hospital for Sick Children | N/A |
| Completed | Retrospective Study on the Outcome of Cleft Palate Repair: Comparing US Surgical and Ethicon Suture Materials NCT00584272 | University of California, Davis | — |
| Completed | Primary Palatoplasty in Pediatric Patients - A Retrospective Review of Surgical Outcomes NCT01380171 | Children's Healthcare of Atlanta | — |
| Completed | Sleep and Behavior in Children With Cleft Palate NCT01046591 | University of Michigan | — |
| Completed | Oral Cleft Prevention Program NCT00397917 | University of Iowa | Phase 3 |
| Completed | Middle Ear Pressure Disregulation in Cleft Palate Patients NCT00423072 | University of Pittsburgh | — |
| Unknown | 3D Imaging of Hard and Soft Tissue in Orthognathic Surgery NCT00285714 | Radboud University Medical Center | N/A |
| Completed | Oral Cleft Prevention Trial in Brazil NCT00098319 | NICHD Global Network for Women's and Children's Health | Phase 3 |
| Completed | Systematic Pediatric Care for Oral Clefts - South America NCT00097149 | NICHD Global Network for Women's and Children's Health | N/A |
| Completed | Cleft Palate Surgery and Speech Development NCT00004639 | University of Florida | Phase 2 |
| Completed | Svangerskap, Arv, Og Miljo (Pregnancy, Heredity and Environment) NCT00340977 | National Institute of Environmental Health Sciences (NIEHS) | — |