| Not Yet Recruiting | Implementing Cognitive Behavioral Therapy for Insomnia (SWELL): Function QUERI 3.0 NCT07216261 | VA Office of Research and Development | N/A |
| Not Yet Recruiting | Internet-Based Cognitive Behavioral Therapy for Insomnia in Persian-Speaking Adults NCT07431034 | Rasool Hamidi Choolabi | N/A |
| Recruiting | Facial Emotion Recognition in Insomnia and Emotional Regulation NCT06251258 | University Hospital, Angers | N/A |
| Not Yet Recruiting | Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic NCT06644573 | Nyree Penn | Phase 1 |
| Recruiting | Evaluation of the Efficacy of E2R Hypnotherapy in the Management of Chronic Insomnia in Primary Care (HypERR) NCT06898099 | Rennes University Hospital | N/A |
| Recruiting | Studying the Neurobiological Mechanisms of Non-specific Chronic Low Back Pain and Chronic Insomnia: a Four-gro NCT06973837 | Vrije Universiteit Brussel | — |
| Not Yet Recruiting | Restorative Effects of Sleep on Everyday Health and Wellbeing: A Treatment Study NCT07156383 | University of Notre Dame | N/A |
| Recruiting | Exploration of the Effectiveness of Vibrational Intervention in Improving Insomnia Symptoms NCT06983275 | Jia Xiu | N/A |
| Recruiting | Transcranial Alternating Current Stimulation for Generalized Anxiety Disorder and Insomnia: An Open-Label Pilo NCT07429578 | University of Sao Paulo | N/A |
| Recruiting | Brief Trial of ACT-i for Adults With Chronic Insomnia NCT07048600 | Babes-Bolyai University | N/A |
| Not Yet Recruiting | A Randomized, Single-Blind Study Evaluating the Efficacy and Cost-Effectiveness of Brief Behavioral Therapy fo NCT06727916 | Nguyen Trai Hospital | N/A |
| Recruiting | Improving Sleep and Reducing Opioid Use in Individuals With Chronic Pain NCT06345872 | University of South Florida | N/A |
| Recruiting | Effects of Sleep Restriction and Stimulus Control in Chronic Insomnia Patients NCT06658184 | Xuanwu Hospital, Beijing | N/A |
| Recruiting | Effects of Cognitive Correction and Stimulus Control in Chronic Insomnia Patients NCT06658158 | Xuanwu Hospital, Beijing | N/A |
| Recruiting | Effects of Relaxation Training and Stimulus Control in Chronic Insomnia Patients NCT06658171 | Xuanwu Hospital, Beijing | N/A |
| Recruiting | Effect of MIT for CI With Anxiety NCT06969053 | Xuanwu Hospital, Beijing | N/A |
| Recruiting | Effects of Tai Chi on Chronic Insomnia Disorder Combined With Hyperarousal/Anxiety NCT06967974 | Xuanwu Hospital, Beijing | N/A |
| Recruiting | Effect of WBT for CI With Depression NCT06968013 | Xuanwu Hospital, Beijing | N/A |
| Recruiting | Effect of Yoga in Chronic Insomnia NCT07419152 | All India Institute of Medical Sciences | N/A |
| Not Yet Recruiting | A Study of Ramelteon in Chinese Patients With Chronic Insomnia NCT06512363 | Nanjing Chia-tai Tianqing Pharmaceutical | Phase 3 |
| Unknown | Safety and Efficacy of Zolpidem in the Long-Term Treatment of Insomnia NCT05456152 | EMS | Phase 3 |
| Suspended | Feasibility and Preliminary Efficacy of Acceptance and Commitment Therapy (ACT) for Sleep Disturbances in Adul NCT05457790 | National Cancer Institute (NCI) | N/A |
| Completed | Effect of Suanzaoren Decoction and Huanglian Wendan Decoction on Biorhythm of Insomnia Patients NCT06467851 | The First Affiliated Hospital with Nanjing Medical University | N/A |
| Recruiting | Digital Cognitive Behavioral Therapy for Insomnia for Chronic Insomnia in Breast Cancer Survivors NCT05813392 | Peking University First Hospital | N/A |
| Unknown | Comparing Insomnia Care As Usual to Digital Augmentation (CICADA) NCT05490550 | Noctem, LLC | N/A |
| Active Not Recruiting | Brief Behavioral Therapy for Insomnia(BBTi) in Middle-aged and Older Adults With Chronic Insomnia NCT06073990 | National Cheng-Kung University Hospital | N/A |
| Completed | Clinical Efficacy and Mechanism of High Definition tDCS Based on dmPFC in the Intervention of Chronic Insomnia NCT06290492 | WANG KAI | N/A |
| Completed | Digital Management of Sleep Health NCT06481423 | Jia Xiu | N/A |
| Active Not Recruiting | The Association Between CBT-I Dose, Sleep Duration, and Fatigue in Breast Cancer Patients NCT05226078 | Abramson Cancer Center at Penn Medicine | N/A |
| Recruiting | Lemborexant vs Zopiclone vs Clonidine for Insomnia Treatment in Chronic Pain Patients NCT05618002 | Salem Anaesthesia Pain Clinic | — |
| Completed | Mirtazapine for Chronic Insomnia in Older Adults NCT05247697 | Centre hospitalier de l'Université de Montréal (CHUM) | Phase 1 |
| Completed | Tai Chi Versus Conventional Exercise to Alleviate Depression in Insomniacs NCT05482646 | The University of Hong Kong | N/A |
| Unknown | FMT Capsules in Treatment of Patients With Insomnia Clinical Research NCT05427331 | Third Military Medical University | N/A |
| Withdrawn | NiteCAPP_HELPS_WD: Improving Sleep and Reducing Opioid Use in Chronic Pain Patients NCT05226026 | University of Missouri-Columbia | N/A |
| Completed | CBT-I or Zolpidem/Trazodone for Insomnia NCT04468776 | California Pacific Medical Center Research Institute | Phase 4 |
| Recruiting | Insomnia Behavioral Intervention Study NCT05301543 | University of Pennsylvania | N/A |
| Unknown | Study for Evaluating the Efficacy of Ciprofol in Patients Under Narcotic Sleep With Chronic Insomnia NCT04958382 | Sichuan Provincial People's Hospital | N/A |
| Unknown | Sleep Time and Insomnia Factors Among Professional Flight Members NCT04761796 | Direction Centrale du Service de Santé des Armées | — |
| Completed | Telepsychology for Benzodiazepines Withdrawal in Adults Suffering From Hypnotic-dependent Insomnia NCT04751851 | Association Nationale de Promotion des Connaissances sur le Sommeil | N/A |
| Completed | DexmedetOmidine Complement Treats Chronic insOmnia and Improves Circadian Rhythm (DOCTOR) NCT04635098 | Ruijin Hospital | N/A |
| Completed | Digital Cognitive Behavioral Therapy for Insomnia (dCBT-I) for Chronic Insomnia :A Randomized Controlled Trial NCT04779372 | Peking University First Hospital | N/A |
| Completed | Neurofeedback Impact on Veterans With mTBI NCT04195685 | VA Office of Research and Development | N/A |
| Completed | Digital Psychological Self-care for Sleep Problems NCT04771234 | Karolinska Institutet | N/A |
| Completed | Enhancing Access to Insomnia (EASI) Care in VA PCMHI Clinics NCT04350866 | VA Office of Research and Development | — |
| Completed | Mindfulness and Compassive Acceptance for Chronic Insomnia in Comparison With CBT NCT05555108 | University of Coimbra | N/A |
| Completed | Treatment of Chronic Insomnia According to Yin Yang Theory and Its Correlation With Circadian Rhythm NCT05452577 | The First Affiliated Hospital with Nanjing Medical University | N/A |
| Recruiting | Interest of Auriculotherapy in the Management of Chronic Insomnia NCT04471168 | Hopital Foch | N/A |
| Unknown | Optimizing the Scalability of Evidence-Based Behavioral Sleep Medicine Practices With a Digital Health Platfor NCT04366284 | Noctem, LLC | N/A |
| Completed | Efficacy of Tai Chi Versus CBT-I in Treating Chronic Insomnia in Older Adults NCT04384822 | The University of Hong Kong | N/A |
| Completed | Effectiveness and Cost-effectiveness of iCBT-I in Clinical Settings NCT04300218 | I.M. Sechenov First Moscow State Medical University | N/A |
| Unknown | Effectiveness of Music Therapy on Sleep Disorders NCT04578860 | Versailles Saint-Quentin-en-Yvelines University | N/A |
| Unknown | A Remote, 9-week Insomnia Treatment Trial to Collect Real World Data for a Digital Therapeutic NCT04325464 | Pear Therapeutics, Inc. | N/A |
| Completed | Naturalistic Monitoring and Treatment of Chronic Insomnia NCT04013321 | Washington State University | N/A |
| Unknown | Xuefu-Zhuyu Capsule for the Treatment of "Qizhi Xueyu Zheng" (Qi Stagnation and Blood Stasis Syndrome) NCT04218487 | Zhong Wang | Phase 4 |
| Active Not Recruiting | Impact of Insomnia Treatment on Brain Responses During Resting-state and Cognitive Tasks NCT04024787 | Concordia University, Montreal | N/A |
| Completed | Brief Behavioral Treatment for Insomnia in Cancer Survivors NCT03810365 | State University of New York at Buffalo | N/A |
| Completed | Alpha-s1 Casein Hydrolysate on Sleep NCT06199596 | Kuang Tien General Hospital | N/A |
| Unknown | Impact of Suvorexant on Sympathetic Nerve Activity and Baroreflex Function in Chronic Insomnia NCT03768713 | Montana State University | Phase 4 |
| Completed | Sleep, Pain and Function in People With Chronic Spinal Pain and Comorbid Insomnia NCT03796481 | University Ghent | — |
| Completed | Zolpidem or Exercise for Insomnia? NCT03160404 | Universidade Federal de Goias | EARLY_Phase 1 |
| Unknown | The Effects of MBSR on Patients With TBI and Chronic Insomnia NCT03560843 | Henry M. Jackson Foundation for the Advancement of Military Medicine | N/A |
| Unknown | Acupuncture Regulates Default Mode Network of Chronic Insomnia Disorder Patients : A fMRI Study NCT03386903 | Beijing Hospital of Traditional Chinese Medicine | N/A |
| Completed | The Study of Combination Use of Melatonin Receptor Agonist for Dose Reduction or Interruptions of Benzodiazepi NCT03461042 | Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan | Phase 4 |
| Completed | Mobile Intervention to Improve Functional Health and Community Engagement of Post-9/11 Veterans With Chronic I NCT03305354 | Northeastern University | N/A |
| Unknown | Effects of Leader Sleep Improvement on Leadership NCT03014960 | University of Washington | N/A |
| Completed | Effects of Exercise and Acupuncture on Chronic Insomnia NCT03171519 | Universidade Federal de Goias | N/A |
| Completed | Internet-based CBT for Insomnia in Chronic Pain NCT03075683 | Uppsala University | N/A |
| Completed | Integrated CBT-I and PE on Sleep and PTSD Outcomes (Impact Study) NCT02774642 | VA Office of Research and Development | N/A |
| Completed | Sleep and Pain Intervention for Chronic Widespread Pain Pilot Study NCT02688569 | University of Missouri-Columbia | N/A |
| Completed | Targeting Sleep in Kids With Autism Spectrum Disorder NCT02755051 | University of Missouri-Columbia | N/A |
| Completed | Implementation of Brief Insomnia Treatments - Clinical Trial NCT02724800 | VA Pittsburgh Healthcare System | N/A |
| Completed | Insomnia Self-Management in Heart Failure NCT02660385 | Yale University | N/A |
| Completed | Mobile Sleep Intervention for OEF, OIF and OND Veterans NCT02392000 | VA Office of Research and Development | N/A |
| Completed | Safety and Efficacy of Chronic Hypnotic Use 2 NCT02456532 | Henry Ford Health System | Phase 4 |
| Completed | Evaluating the Efficacy of the Management of an Online Program of Cognitive Behavioral Therapy for Primary Ins NCT02539862 | University Hospital, Montpellier | N/A |
| Completed | REST: Restoring Effective Sleep Tranquility in College Veterans With Service-Related Injuries NCT02871414 | Colorado State University | N/A |
| Unknown | Cognitive Behavioral Therapy for Insomnia Among Different Types of Shift Workers NCT02523079 | Finnish Institute of Occupational Health | N/A |
| Terminated | CBT-I Intervention for Insomnia in Newly Diagnosed Cancer Patients NCT02410564 | Virginia Commonwealth University | N/A |
| Completed | Pilot Study to Clinical Evaluate Lacrima Medical Device in Insomnia Patients NCT02236845 | Lacrima Medical LTD | N/A |
| Completed | Impact of Hyperarousal on Simple and Complex Cognitive Task Performance Among Insomnia Sufferers NCT02290405 | Jack Edinger, PhD | — |
| Completed | Impact of Homeopathy for Persistent Insomnia in Patients With Cancer NCT02515006 | Adwin Life Care | N/A |
| Completed | The Effectiveness of Online Treatment for Insomnia in Cancer Survivors NCT02272712 | Ottawa Hospital Research Institute | N/A |
| Completed | Cognitive Behavioral Therapy (CBT)-Insomnia for Lung Cancer NCT02121652 | State University of New York at Buffalo | N/A |
| Completed | Hyper-Arousal in Chronic Primary Insomnia NCT02048878 | University of Chicago | — |
| Completed | A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Bayesian Adaptive Randomization D NCT01995838 | Eisai Inc. | Phase 2 |
| Completed | Piloting an Internet-based Therapy for Insomnia in a Population of Veterans With Substance Use Disorders NCT01949389 | VA Connecticut Healthcare System | N/A |
| Completed | Brief Behavioral Treatment of Insomnia in Military Veterans: Phase 2 (BBTIMVII) NCT00840255 | University of Pittsburgh | N/A |
| Unknown | Effect of Rozerem on the Perception of GERD Symptoms in Patients With Chronic Insomnia. NCT01128582 | Southern Arizona VA Health Care System | Phase 3 |
| Completed | Chamomile for Chronic Primary Insomnia NCT01286324 | University of Michigan | Phase 2 |
| Completed | Brief Behavioral Treatment of Insomnia in Military Veterans: Phase 1 NCT00679406 | University of Pittsburgh | N/A |
| Completed | Cognitive-Behavior Therapy for Insomnia NCT00869934 | Laval University | Phase 4 |
| Completed | Mindfulness Versus Pharmacotherapy for Chronic Insomnia: A Pilot Study NCT00515177 | University of Minnesota | Phase 2 / Phase 3 |
| Completed | Facilitation of Zolpidem (≥10 mg) Discontinuation Through Use of Ramelteon in Subjects With Chronic Insomnia NCT00492232 | Takeda | Phase 4 |
| Completed | Effects of Chronic Insomnia on the Neuroendocrine Regulation of Glucose and Lipid Metabolism NCT00442624 | University Hospital, Basel, Switzerland | — |
| Completed | Subjective Efficacy of Ramelteon on Sleep in Adults With Chronic Insomnia. NCT00414102 | Takeda | Phase 4 |
| Terminated | Treating Chronic Insomnia in Breast Cancer Patients NCT00337272 | Accelerated Community Oncology Research Network | Phase 4 |
| Completed | Efficacy and Safety of Ramelteon in Subjects With Mild to Moderate Alzheimer's Disease NCT00325728 | Takeda | Phase 2 |
| Completed | Long-Term Efficacy and Safety of Ramelteon in Adults With Chronic Insomnia. NCT00247390 | Takeda | Phase 3 |
| Terminated | Efficacy of Ramelteon in Adults With Chronic Insomnia NCT00672724 | Takeda | Phase 3 |
| Completed | Study of Efficacy of Ramelteon in Adults With Chronic Insomnia NCT00671125 | Takeda | Phase 3 |
| Completed | Safety and Efficacy of Ramelteon in Elderly Subjects With Chronic Insomnia NCT00671255 | Takeda | Phase 3 |
| Completed | Ramelteon in Adults With Chronic Insomnia NCT00671567 | Takeda | Phase 3 |
| Completed | Safety and Efficacy of Ramelteon in Elderly Subjects With Chronic Insomnia. NCT00671294 | Takeda | Phase 3 |
| Completed | Efficacy and Safety of Ramelteon on Chronic Insomnia NCT00915135 | Takeda | Phase 2 |