| Recruiting | A Clinical Prediction Model for Surgical Site Infection After Central Nervous System Tumor Surgery NCT07378683 | Ming Yang | N/A |
| Recruiting | Somatic Mosaicism in Twins Discordant for Childhood Cancer NCT06054295 | Children's Oncology Group | — |
| Not Yet Recruiting | Effect and Safety of Ocoxin Oral Solution on the Quality of Life of Paediatric Patients With Advanced Stage So NCT06363201 | Catalysis SL | N/A |
| Recruiting | A Study of Avutometinib for People With Solid Tumor Cancers NCT06104488 | Memorial Sloan Kettering Cancer Center | Phase 1 |
| Recruiting | Brain Slice Explants to Predict Drug Response in Brain Tumors NCT05978557 | UNC Lineberger Comprehensive Cancer Center | — |
| Completed | Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas System NCT04743310 | John Yu | Phase 2 |
| Recruiting | ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS NCT04732065 | Sabine Mueller, MD, PhD | Phase 1 |
| Recruiting | Tissue Collection for Drug Screening and Bioanalysis NCT04852354 | Weill Medical College of Cornell University | — |
| Recruiting | Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Mid NCT04185038 | Seattle Children's Hospital | Phase 1 |
| Terminated | Mapping Draining Lymph Nodes in CNS Malignancies NCT04096716 | Washington University School of Medicine | Phase 1 |
| Active Not Recruiting | Biological Characterisation of High Risk CHildhood Cancer in Children, Adolescents and Young Adults (MICCHADO) NCT03496402 | Institut Curie | N/A |
| Recruiting | SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry NCT03452774 | Massive Bio, Inc. | — |
| Active Not Recruiting | Safety and Dose Finding Study of Neratinib in Children and Young Adults With Cancer That Has Returned or Not R NCT02932280 | Memorial Sloan Kettering Cancer Center | Phase 1 / Phase 2 |
| Completed | Medical Marijuana in the Pediatric Central Nervous System Tumor Population NCT03052738 | University of Colorado, Denver | — |
| Completed | Medical and Surgical Management of Patients With Brain Metastases NCT03981016 | Institut du Cancer de Montpellier - Val d'Aurelle | N/A |
| Completed | Dendritic Cell-based Immunotherapy for Advanced Solid Tumours of Children and Young Adults NCT02496520 | Clinica Universidad de Navarra, Universidad de Navarra | Phase 1 / Phase 2 |
| Recruiting | Integrated Cancer Repository for Cancer Research NCT02012699 | University of Nebraska | — |
| Completed | Longitudinal Study of Biomarkers NCT01595126 | Ann & Robert H Lurie Children's Hospital of Chicago | — |
| Completed | Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ C NCT00716976 | Children's Oncology Group | Phase 3 |
| Completed | Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed P NCT00085098 | Children's Oncology Group | Phase 3 |
| Completed | Radiation Therapy in Treating Young Patients With Gliomas NCT00238264 | Children's Oncology Group | Phase 2 |
| Completed | High-Dose Chemotherapy Plus Autologous Stem Cell Transplantation Compared With Intermediate-Dose Chemotherapy NCT00078988 | Children's Oncology Group | Phase 3 |
| Completed | Carboplatin, Vincristine, and Temozolomide in Treating Children With Progressive and/or Symptomatic Low-Grade NCT00077207 | Children's Oncology Group | N/A |
| Completed | Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergon NCT00027846 | Children's Oncology Group | Phase 2 |
| Completed | Temozolomide Plus Lomustine Followed by Radiation Therapy in Treating Patients With High-Grade Malignant Gliom NCT00006024 | Children's Oncology Group | Phase 1 |
| Completed | Combination Chemotherapy Followed by Bone Marrow and/or Peripheral Stem Cell Transplantation in Treating Patie NCT00002594 | Children's Oncology Group | Phase 2 |
| Available | Expanded Access [11C] Methionine PET Imaging NCT05511714 | St. Jude Children's Research Hospital | — |