NCT04096716

Mapping Draining Lymph Nodes in CNS Malignancies

• Status: Terminated
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 14 (actual)
• Sponsor: Washington University School of Medicine · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this research study is to determine whether the lymph nodes that drain a brain tumor can be detected by imaging after injection of a substance called Tc-99m tilmanocept directly into the brain tissue around the tumor. Tc-99m tilmanocept is a radioactive substance that is used to find lymph nodes by injecting it and then scanning the body with a device that can trace its radioactivity. In this study, the investigators are looking to see how long it takes the Tc-99m tilmanocept to travel from the tumor to the lymph nodes. The investigators will be using it to map lymph nodes as they relate to specific brain areas.

Conditions

• Central Nervous System Neoplasms
• Central Nervous System Tumor

Interventions

Type	Name	Description
DRUG	Tc-99m tilmanocept	Tc-99m tilmanocept is a radioactive diagnostic agent.

Timeline

• Start date: 2019-12-03
• Primary completion: 2022-04-30
• Completion: 2022-04-30
• First posted: 2019-09-20
• Last updated: 2023-12-21

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study