| Recruiting | Economic-demographic Assessment of the Aseptic Mobilization of Knee Prostheses Through the RIPO Registry and R NCT06821581 | Istituto Ortopedico Rizzoli | — |
| Not Yet Recruiting | MRI Role in Knee Hemophilic Arthopathy NCT07233122 | Assiut University | — |
| Recruiting | Impact of Dexamethasone Route on Pain and Inflammation in iPACK With ACB for Knee Arthroplasty NCT07180953 | Poznan University of Medical Sciences | Phase 4 |
| Withdrawn | Investigating the Effect of Dronabinol on Post-surgical Pain NCT04099355 | New York State Psychiatric Institute | EARLY_Phase 1 |
| Enrolling By Invitation | How Many Dexamethasone Doses Should Be Given Perioperatively? NCT06715709 | Mayo Clinic | Phase 4 |
| Completed | Comparison of Postoperative Pain in Primary Cemented Total Knee Arthroplasty With or Without Drain NCT07175883 | Hospital Universitario Reina Sofia de Cordoba | N/A |
| Recruiting | Total Versus Robotic Assisted Unicompartmental Knee Replacement NCT05290818 | NHS Lothian | N/A |
| Not Yet Recruiting | Preliminary Muscle Contraction in the Rehabilitation and Prevention of Degenerative Pain in the Locomotor Syst NCT06415825 | Medical University of Sofia | N/A |
| Active Not Recruiting | Incidence and Risk Factors for Post-Anesthetic Morphine Titration in Recovery Room After Hip and Knee Arthropl NCT06832995 | Hôpital Privé Sévigné | — |
| Completed | Fascia Iliaca Compartment Block and IPACK Block in Total Knee Arthroplasty NCT06125067 | Ankara Ataturk Sanatorium Training and Research Hospital | — |
| Unknown | Nirvana Super Pro Supplementation in Orthopedic Surgery Patients NCT06203691 | Nirvana Water Sciences Corp | N/A |
| Unknown | Comparison of Two Different Regional Analgesia Techniques for Patients Undergoing Total Knee Arthroplasty NCT06179641 | Centre Hospitalier Universitaire Vaudois | N/A |
| Unknown | Weight Change and the Risk of Chronic Pain Following Hip and Knee Arthroplasties NCT06024161 | Bispebjerg Hospital | — |
| Completed | Comparative Effect of Mechanical and Functional Alignment in Bilateral Total Knee Arthroplasty on Ankle Alignm NCT06259032 | Department of Medical Services Ministry of Public Health of Thailand | N/A |
| Completed | The Effect of Whole-Body Vibration Treatment Before Total Knee Arthroplasty NCT05967637 | Gazi University | N/A |
| Completed | A Multi-Component Weight Loss Intervention to Improve Outcomes of Total Knee Replacement NCT05853497 | University of Kansas Medical Center | N/A |
| Terminated | Late-initiated Blood Flow Restricted Rehabilitation Exercises After Total Knee Replacement NCT05770934 | University of Aarhus | N/A |
| Completed | Effect of Plugging the Registration Pin Tract in Robotic-assisted Knee Surgery NCT05638386 | Reinier Haga Orthopedisch Centrum | — |
| Completed | Peripheral Nerve Blocks and Postoperative Pain and Mobilization After Total Knee Arthroplasty NCT07442123 | Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital | — |
| Completed | Opioid Education in Total Knee Arthroplasty NCT05593341 | Hospital for Special Surgery, New York | N/A |
| Unknown | Alteration of Thrombelastography and Coagulation Function in Patients Undergoing Total Knee Arthroplasty With NCT05490160 | RenJi Hospital | — |
| Completed | Trail-running After Knee or Hip Arthroplasty NCT05470634 | Centre Hospitalier Universitaire de la Réunion | — |
| Recruiting | Pre-operative Inspiratory Muscle Strength Training in Total Joint Surgery NCT05381818 | University of Florida | N/A |
| Unknown | Protocol for a Multicenter Study on (Cost)Effectiveness of the Back At Work After Surgery (BAAS): a Clinical P NCT05690347 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | — |
| Completed | Muscle Strength and Total Knee Replacement NCT05248815 | Vastra Gotaland Region | — |
| Completed | Experience of Use and Biopsychosocial Effects of Robotic and Virtual Reality Devices in Neuromotor Rehabilitat NCT05399043 | Istituti Clinici Scientifici Maugeri SpA | N/A |
| Recruiting | A Comparison Of Primary TKA Rehabilitation Using A Smart Orthotic Versus Outpatient Physical Therapy NCT04924205 | Nicolas Noiseux, MD, MS, FRCSC | N/A |
| Completed | Effects Of Supervised Sensorimotor Training Through Telerehabilitation Monitoring After Total Knee Arthroplast NCT05018494 | Riphah International University | N/A |
| Active Not Recruiting | Triathlon All-Polyethylene Tibia Outcomes Study NCT04636190 | Stryker Orthopaedics | N/A |
| Completed | Randomized Controlled Trial Comparing Robotic-Assisted Versus Conventional Total Knee Arthroplasty NCT07212296 | Hospital de Terrassa | N/A |
| Completed | RelieVRx for Total Knee Arthroplasty (TKA) for the Reduction of Acute Postoperative Pain and Opioid Use NCT04010266 | AppliedVR Inc. | N/A |
| Unknown | Magnesium Sulfate and Neuroendocrine Hormone NCT04514731 | Seoul National University Hospital | Phase 4 |
| Completed | Dexmedetomidine on Tourniquet Induced -Systemic Effects NCT04307290 | Wonkwang University Hospital | Phase 4 |
| Unknown | Effect of Preoperative Steroid in Total Knee Arthroplasty NCT04084912 | Assiut University | Phase 3 |
| Completed | 7T MRI to Evaluate Cartilage Defects in the Knee NCT04118023 | The Methodist Hospital Research Institute | — |
| Terminated | Cardiac and Renal Biomarkers in Arthroplasty Surgery NCT03940651 | Washington University School of Medicine | Phase 4 |
| Completed | Prevention of Postoperative Urinary Retention With Treatment of Tamsulosin 5 Days Prior to Lower Limb Arthropl NCT03808155 | Kantonsspital Graubünden | Phase 4 |
| Completed | Does Tourniquet Use Have an Effect on Pain and Function After Total Knee Arthroplasty NCT04733716 | Umraniye Education and Research Hospital | N/A |
| Completed | NSS-2-BRIDGE Study for Total Knee and Hip Arthroplasties, Bariatric, and Kidney Transplant Surgeries NCT03834142 | Jacques E. Chelly | N/A |
| Withdrawn | Assessing if Cryoneurolysis Improves Prehabilitation and Decreases Pain After Surgery With Less Opioid Use in NCT03836313 | Brigham and Women's Hospital | N/A |
| Recruiting | Total Knee Arthroplasty: Fast Track Protocol is the Future? NCT03869996 | Istituto Ortopedico Rizzoli | N/A |
| Unknown | Effect Of The Use Of Navigation In The Alignment Obtained When Performing A Total Knee Arthroplasty In Obese P NCT03865524 | Pedro-José Torrijos-Garrido | N/A |
| Completed | Does the Use of Intrathecal Morphine Increase the Length of Hospital Stay in Fast Track Orthopedic Procedures? NCT05105074 | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | N/A |
| Unknown | Validation of Consumer Activity Monitors in Postoperative Total Arthroplasty Patients NCT03958370 | Benaroya Research Institute | — |
| Completed | Results of the Application of the Clinical Pathway of Intensified Recovery Surgery for Adults in the Processes NCT05338255 | Universidad de Zaragoza | — |
| Unknown | Prediction Model of Acute Postoperative Pain in Bilateral Total Knee Replacement Arthroplasty Patient NCT03765723 | Seoul National University Hospital | — |
| Completed | Infrapatellar Fat Pad Preservation Versus Resection on Clinical Outcomes After Total Knee Arthroplasty(IPAKA) NCT03763448 | Zhujiang Hospital | N/A |
| Completed | Total Knee Arthroplasty and Clinical Findings NCT04481711 | Karadeniz Technical University | N/A |
| Active Not Recruiting | The Effect of Light Therapy on Post-Surgical Pain NCT03674697 | University of Arizona | N/A |
| Completed | A Prospective Clinical Trial Comparing Serum Mast Cell Tryptase (SMCT) Levels to Arthrofibrosis Rates Among Pr NCT03598829 | Mayo Clinic | — |
| Completed | Evaluation of Static Postural Balance in Children With Hemophilia and Its Relationship With Joint Health NCT04406519 | Necmettin Erbakan University | — |
| Completed | Study to Reduce Sitting in Older Adults Undergoing Hip or Knee Replacements NCT03740412 | University of Birmingham | N/A |
| Unknown | Post-operative Rehabilitation of Total Knee Arthroplasty With Applications on Smart Phone NCT03365427 | Peking University People's Hospital | N/A |
| Unknown | Diagnosis of Periprosthetic Joint Infection and the Common Pathogens, Durg-resistance in Periprosthetic Joint NCT03365323 | Peking University People's Hospital | — |
| Completed | Antibiotic Prophylaxis in Patients Undergoing Elective Total Knee Arthroplasty- Multi-center Trial NCT03283878 | Duke University | Phase 4 |
| Completed | A Survey on Blood Transfusions in Major Artrhoplasty Operations NCT03282201 | Diskapi Teaching and Research Hospital | — |
| Terminated | Economic and Functional Impact of Peri-Operative Bracing for Primary Total Knee Arthroplasty (TKA) NCT03260699 | The Cleveland Clinic | N/A |
| Completed | Stated-Preferences in Knee Arthroplasty NCT03058380 | Duke University | — |
| Completed | Outpatient Total Joint Arthroplasty in Dedicated Daycare Facility vs Standard Patient Ward NCT03896282 | Hvidovre University Hospital | N/A |
| Completed | Meditation and Opioid Consumption in Total Joint Replacement Patients Undergo Primary Total Hip and Knee Repla NCT05669066 | Beth Israel Deaconess Medical Center | N/A |
| Completed | Rehabilitation for Total Knee Replacement: a Novel Biofeedback System Versus Conventional Home-based Rehabilit NCT03047252 | Sword Health, SA | N/A |
| Completed | IPACK Nerve Block for Total Knee Arthroplasty NCT03921034 | Ochsner Health System | Phase 4 |
| Unknown | Comparison of Joint Awareness Between Fixed-bearing and Mobile-bearing Total Knee Arthroplasty Using Titanium- NCT04684160 | The Catholic University of Korea | N/A |
| Terminated | Opioid Consumption After Hospital Discharge in Orthopedic Surgery NCT03185117 | Ohio State University | — |
| Completed | Evaluation of the Duration of Bupivacaine Spinal Block in Orthopedic Procedures With and Without Epinephrine W NCT02619409 | Medical University of South Carolina | N/A |
| Completed | Comparative Outcomes Between Image-based Versus Imageless Robot-assisted Unicondylar Knee Arthroplasty NCT03954912 | Ramathibodi Hospital | N/A |
| Completed | Prospective, Assessment of Vitamin D and Calcium Supplementation, Improvement of Nutritional Status and Preope NCT04291833 | Jagiellonian University | N/A |
| Completed | Comparison of Two Anatomic Landmarks With Ultrasonography in Spinal Anesthesia NCT02330185 | Diskapi Yildirim Beyazit Education and Research Hospital | Phase 4 |
| Completed | Tranexamic Acid Dosing for Total Joint Arthroplasty NCT02584725 | Columbia University | Phase 4 |
| Terminated | Evaluation of Weight Bearing After Total Hip and Knee Replacement NCT01135160 | Kantonsspital Münsterlingen | — |
| Completed | Adductor Canal Block Versus Femoral Nerve Block for Total Knee Arthroplasty NCT03133481 | University of Alabama at Birmingham | Phase 3 |
| Completed | The Impaction of Exercise Training on Bone Mineral Density in Patients After Total Knee Arthroplasty NCT02928562 | Chang Gung Memorial Hospital | N/A |
| Completed | Pinless-Navigated Versus Conventional Total Knee Arthroplasty NCT01676038 | Singapore General Hospital | N/A |
| Completed | Analysis of Standard Versus Barbed Sutures in Primary Total Knee Arthroplasty. NCT01320371 | University of Utah | — |
| Withdrawn | Optetrak Posterior Stabilized Versus Optetrak Hi-Flex NCT00808613 | Exactech | N/A |
| Terminated | Scorpio® Cruciate Retaining (CR) Outcomes Study NCT00965146 | Stryker Orthopaedics | N/A |