NCT02619409

Evaluation of the Duration of Bupivacaine Spinal Block in Orthopedic Procedures With and Without Epinephrine Wash

Evaluation of the Duration of Bupivacaine Spinal Block as the Primary Anesthetic for Orthopedic Procedures With and Without Epinephrine Wash

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Medical University of South Carolina · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Bupivacaine spinal is commonly performed as the primary anesthetic for orthopedic procedures. In some cases the duration of the block is inadequate. An epinephrine wash is sometimes performed to prolong the duration of the block. The epinephrine wash may prolong the duration of the block, and if it does, to what extent?

Conditions

• Arthropathy of Hip
• Arthropathy of Knee

Interventions

Type	Name	Description
DRUG	Bupivacaine Only	The bupivacaine only group will receive bupivacaine 0.5% 3cc plus sterile saline 0.1cc.
DRUG	EPI25	The EPI25 group will receive bupivacaine 0.5% 3cc, epinephrine 1:1000 0.025cc, and sterile saline 0.075cc.
DRUG	EPI50 group	The EPI50 group will receive bupivacaine 0.5% 3cc, epinephrine 1:1000 0.05cc, and sterile saline 0.05cc
DRUG	EPI75 group	The EPI75 group will receive bupivacaine 0.5% 3cc, epinephrine 1:1000 0.075cc, and sterile saline 0.025%.
DRUG	EPI100 group	The EPI100 group will receive bupivacaine 0.5% 3cc, and epinephrine 1:1000 0.1cc.

Timeline

• Start date: 2016-02-11
• Primary completion: 2016-10-20
• Completion: 2016-10-20
• First posted: 2015-12-02
• Last updated: 2023-06-06
• Results posted: 2018-07-17

Locations

1 site across 1 country: United States