| Not Yet Recruiting | Effects of a Targeted Prevention Program on Change-of-Direction Biomechanics and Performance in Elite Female S NCT07523178 | University of Liege | N/A |
| Not Yet Recruiting | Sports Rehabilitation Therapy for Knee Joint Sports Injuries: A Case Study of Anterior Cruciate Ligament Injur NCT07423819 | Peking University Third Hospital | N/A |
| Recruiting | ACL Reconstruction With Shark Screw® or Biocomposite-interference Screws NCT06357091 | Alexander Rofner-Moretti | N/A |
| Recruiting | Comparison of Bone-patellar Tendon-bone and Patellar Tendon-bone Grafts in ACL Reconstruction NCT07475351 | Universidad de Granada | N/A |
| Completed | Relationship Between Muscle Strength and Balance NCT07419750 | Biruni University | — |
| Not Yet Recruiting | Comparison of Quadriceps and Semitendinosus Grafts in ACL Reconstruction Using Data From the Danish Knee Ligam NCT06980285 | Abdirahman Hassan Omar | — |
| Enrolling By Invitation | Exercise Loading Biology Post-Traumatic OsteoArthritis Study - a Pilot and Feasibility Study NCT06892899 | May Arna Risberg | — |
| Recruiting | Virtual Reality Mindfulness Meditation After ACL Reconstruction NCT05527171 | University of North Carolina, Chapel Hill | N/A |
| Completed | Effects of Low-intensity Strength Training With Concomitant Blood Flow Restriction on Pain Perception in Patie NCT06699264 | Praxisklinik Rennbahn AG | N/A |
| Completed | Effectiveness of Rehabilitation After Arthroscopic ACL Reconstruction Using Inertial Exercises NCT06726044 | University in Zielona Góra | N/A |
| Completed | Eccentric Phase Biomechanics of the Countermovement Jump After Anterior Cruciate Ligament Reconstruction NCT07448064 | Haute Ecole ARC Sante | — |
| Completed | Arthroscopic Anterior Cruciate Ligament Reconstruction by Hamstring Graft With and Without Platelet-Rich Plasm NCT07269522 | Muhammad Aamir Latif | N/A |
| Completed | Sensory Deficit Following ACL Reconstruction: PRF Pilot Study NCT07257666 | University of Belgrade | — |
| Completed | Remnant Preservation and Tibial Tunnel Widening After ACL Reconstruction NCT07236593 | Cairo University | N/A |
| Active Not Recruiting | STABILITY 2: Anterior Cruciate Ligament Reconstruction +/- Lateral Tenodesis With Patellar vs Quad Tendon NCT03935750 | University of Pittsburgh | N/A |
| Completed | MDR EZ Pass and Precision Flexible Reamer NCT03914703 | Zimmer Biomet | — |
| Terminated | Gait Retraining Enhances Athletes' Technique NCT03918681 | Keller Army Community Hospital | N/A |
| Unknown | Back in the Game: a Smartphone Application to Support Athletes Returning to Sport After Serious Injury NCT03959215 | Karolinska Institutet | N/A |
| Completed | Evaluation of the Effect of Using WeChat Applet to Intervene in the Home Functional Exercise of Patients After NCT04957810 | Peking University Third Hospital | N/A |
| Completed | MiACLR: Michigan Initiative for Anterior Cruciate Ligament Rehabilitation NCT03626857 | University of Michigan | N/A |
| Completed | Nonopioid Analgesia After Anterior Cruciate Ligament Reconstruction NCT03818932 | Henry Ford Health System | Phase 2 / Phase 3 |
| Terminated | Treatment of Anterior Ligament Rupture With Internal Brace Repair - A Prospective Randomised Controlled Study. NCT03800225 | Aarhus University Hospital | N/A |
| Completed | Definition of Biomechanical Indices Measurable During Sport Movements for the Prevention of Primary and Second NCT03840551 | Istituto Ortopedico Rizzoli | N/A |
| Completed | Functional and Self-reported Outcomes in Participants With a History of Musculoskeletal Knee Injury NCT03617991 | Johanna M. Hoch | N/A |
| Completed | Acupuncture ACL (Anterior Cruciate Ligament) NCT03711734 | Hospital for Special Surgery, New York | N/A |
| Completed | Combined Saphenous Nerve and IPACK Blocks Versus Infiltration Analgesia After Anterior Cruciate Ligament Recon NCT03680716 | Centre Hospitalier Universitaire Vaudois | N/A |
| Completed | Pain Control for Anterior Cruciate Ligament Reconstruction Patients With Adductor Canal or Femoral Perineural NCT03208478 | Stanford University | N/A |
| Unknown | WEakness and Atrophy: isoKinetic With Surface Electromyography Assessment in ACL Surgery NCT03200678 | Direction Centrale du Service de Santé des Armées | N/A |
| Active Not Recruiting | The BEAR III Trial for Bridge-Enhanced ACL (Anterior Cruciate Ligament) Restoration NCT03348995 | Miach Orthopaedics | N/A |
| Active Not Recruiting | Motor Imagery to Facilitate Sensorimotor Relearning After ACL Injury NCT03473821 | Lund University | N/A |
| Completed | Reduction of Risk Factors for ACL Re-injuries Using a Novel Biofeedback Approach NCT03273673 | Virginia Polytechnic Institute and State University | N/A |
| Completed | Functional Resistance Training to Improve Knee Function After ACL Reconstruction NCT03282565 | University of Michigan | N/A |
| Completed | Protective Role of Muscle Function for Early Features of Knee Osteoarthritis After Anterior Cruciate Ligament NCT03473873 | Lund University | — |
| Completed | Quadrupled Semitendinosus Graft in Anterior Cruciate Ligament Reconstruction NCT03433170 | Fundacion Clinica Valle del Lili | N/A |
| Enrolling By Invitation | Biologic Augmentation With Mesenchymal Stem Cells in Patients Undergoing Anterior Cruciate Ligament Reconstruc NCT04650568 | Rush University Medical Center | N/A |
| Completed | A Novel Analgesia Technique for ACL Reconstruction NCT03292926 | Hospital for Special Surgery, New York | Phase 4 |
| Completed | Popliteal Plexus Block for Postoperative Pain After ACL Reconstruction NCT03130049 | University of Aarhus | N/A |
| Completed | Conditioning Brain Responses to Improve Thigh Muscle Function After Anterior Cruciate Ligament Reconstruction NCT03209531 | University of Michigan | N/A |
| Completed | On-Q Catheter Caregiver Education NCT03372889 | University of Colorado, Denver | N/A |
| Unknown | Long-term Follow-up of Anterior Cruciate Ligament Injury NCT03182647 | Linkoeping University | — |
| Unknown | The Functional Status of Anterior Cruciate Ligament Reconstruction (ACLR) Patients at Discharge From Rehabilit NCT03047187 | University of Salford | — |
| Completed | Factors Affecting the Speed of Recovery After ACL Reconstruction NCT03770806 | University of Washington | N/A |
| Unknown | Mechanical Perturbation Training for ACL Injury Prevention NCT03080402 | University of Delaware | N/A |
| Unknown | The Effects of Neuromuscular Exercise Training on Core Stability and Hip Strength in Healthy Adolescent Female NCT03012711 | University of Manitoba | N/A |
| Unknown | ACL SNNAP Trial: ACL Surgery Necessity in Non Acute Patients NCT02980367 | University of Oxford | N/A |
| Completed | Effect of Dual Tasks on Gait Symmetry After Anterior Cruciate Ligament Reconstruction NCT04461145 | Peking University Third Hospital | N/A |
| Completed | ACL Versus ALL + ACL Study NCT03740022 | Ascopharm Groupe Novasco | N/A |
| Unknown | Natural Course and Recovery After ACL-injury NCT02931084 | Linkoeping University | — |
| Completed | Blood Flow Restriction to Improve Muscle Strength After ACL Injury NCT03141801 | University of Michigan | N/A |
| Completed | Arthroscopic ACL Reconstruction: Hamstring Versus Quadriceps NCT04137250 | Universidad Autonoma de Nuevo Leon | N/A |
| Completed | Effect of Rehabilitation Programs Based on Eccentric Exercise of Knee Extensor Muscles in Isotonic and Isokine NCT02961543 | Federal University of Health Science of Porto Alegre | N/A |
| Completed | Clinical Comparison of Femoral Nerve Versus Adductor Canal Block Following Anterior Ligament Reconstruction NCT03704376 | The University of Texas Health Science Center, Houston | Phase 4 |
| Unknown | Light Load Blood Flow Restriction Training in Anterior Cruciate Ligament Reconstruction Patient Rehabilitation NCT03419169 | University College London Hospitals | N/A |
| Unknown | Single Versus Double Hamstring Harvest for Anterior Cruciate Ligament Reconstruction NCT03626883 | Rafał Kamiński | N/A |
| Completed | Differential Biomechanical Effects of an ACL Injury Prevention Program in Women's Basketball and Soccer Player NCT02530333 | High Point University | N/A |
| Completed | Effects of Elastic Therapeutic Tape on Biomechanical Changes of Knee Joint During Drop Vertical Jump in ACL In NCT02271061 | Mahidol University | N/A |
| Active Not Recruiting | Bridge-Enhanced ACL Repair-Safety Study (BEAR Trial) NCT02292004 | Miach Orthopaedics | N/A |
| Active Not Recruiting | Acute Anterior Cruciate Ligament Rupture; RecOnsTruction Or Repair? NCT02310854 | Orthopedisch Centrum Oost Nederland | N/A |
| Unknown | Clinical Outcome Following Arthroscopic Knee Surgery NCT03700996 | The University of Texas Health Science Center, Houston | — |
| Unknown | The Effect of Knee Flexion Angle for Graft Fixation During Single-Bundle Anterior Cruciate Ligament Reconstruc NCT02111759 | University of Toronto Orthopaedic Sports Medicine | N/A |
| Completed | The Effect of Knee Flexion Angle for Graft Fixation During Single-Bundle Anterior Cruciate Ligament Reconstruc NCT03875807 | Women's College Hospital | N/A |
| Unknown | Maximum Oxygen Uptake in ACL-injured Professional Soccer Players NCT02674282 | University of Sao Paulo | N/A |
| Completed | Optimizing Plyometric Training for Functional Recovery Post-ACL Reconstruction NCT02148172 | University of Montana | N/A |
| Completed | Effect of Resistance Training on Jump Landing Mechanics in Young Female Athletes NCT02043275 | University of Manitoba | N/A |
| Completed | Synthetic Bone Graft Substitute vs. Autologous Spongiosa in Revision Anterior Cruciate Ligament Reconstruction NCT02845141 | Berufsgenossenschaftliche Unfallklinik Ludwigshafen | N/A |
| Completed | Anterior Cruciate Ligament (ACL) Tunnel Widening Comparing All-inside and Interference Screw Fixation Techniqu NCT02052856 | University of British Columbia | — |
| Terminated | Anterior Cruciate Ligament Reconstruction: Residual Rotational Laxity for Single Versus Double Bundle Techniqu NCT01377129 | Centre Hospitalier Universitaire de Nīmes | N/A |
| Withdrawn | Decreasing Knee Injury Risk Factors With Neuromuscular Training NCT01433718 | Ohio University | N/A |
| Completed | Single- vs. Double-Bundle ACL Reconstruction NCT01319409 | University of Pittsburgh | Phase 2 |
| Unknown | Therapeutic Effects of Cryotherapy on Arthrogenic Muscle Inhibition in Patients With Cruciate Ligament Reconst NCT01273649 | National Taiwan University Hospital | N/A |
| Unknown | Anterior Cruciate Ligament Reconstruction Using Single Bundle and Double Bundle Techniques NCT01358656 | Vita Care | N/A |
| Completed | Electrical Stimulation and Eccentric Exercise for Anterior Cruciate Ligament (ACL) Injury NCT01555567 | University of Michigan | N/A |
| Completed | Safety and Efficacy Study of MSB-CAR001 in Subjects 6 Weeks Post an Anterior Cruciate Ligament Reconstruction NCT01088191 | Mesoblast, Ltd. | Phase 1 / Phase 2 |
| Completed | Preemptive Analgesia in Cruciate Reconstruction NCT01017380 | Prince of Songkla University | Phase 3 |
| Completed | Comparison of Three Methods for Anterior Cruciate Ligament Reconstruction NCT00529958 | University of Calgary | N/A |
| Completed | Nonsurgical or Surgical Treatment of ACL Injuries NCT02115451 | Oslo University Hospital | — |
| Completed | Bone Tunnel Widening Following ACL Reconstruction NCT00198042 | Hospital for Special Surgery, New York | N/A |