NCT03182647

Long-term Follow-up of Anterior Cruciate Ligament Injury

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 300 (estimated)
• Sponsor: Linkoeping University · Other Government
• Sex: All
• Age: 47 Years – 77 Years
• Healthy volunteers: Not accepted

Summary

Anterior cruciate ligament (ACL) rupture is one of the most common sports-related knee injuries. Because it is such a significant injury - requiring a long period of rehabilitation before the injured person is ready to return to physical activity, the burden of injury is high. This can help to explain why so much of orthopaedic research is devoted to evaluating the outcomes of ACL injury. However, while there has been extensive study of short-term (up to 5 years after injury) outcomes, few studies have followed patients beyond 15 years after their ACL injury. This is important because long-term follow-up can provide key insights to guide the information provided to newly injured patients (e.g. to help set realistic expectations of what the injured person can expect of their knee function in the future), and help us evaluate the efficacy of previous treatments. The primary aim is to assess the influence of an acute ACL injury on knee function and quality of life, 32-37 years after the index injury. Approximately 300 patients injured between 1980 and 1985 will be invited to participate in the study. Patient- and clinician-reported outcomes, and radiographic osteoarthritis will be evaluated.

Detailed description

Patients injuring their ACL between 1980 and 1985 have periodically been followed since the injury. Now, we plan to contact all patients and invite them to participate. The patients will be asked to 1. complete a questionnaire battery 2. visit the movement laboratory at Linköping University for an objective assessment of knee function and 3. have an x-ray of both knee joints. Baseline information including associated injuries, treatment and activity level exist for all the patients. At that time, rehabilitation was normally completed after 4-6 months for non-operatively treated patients, and nine months after ACL surgery.

Conditions

• Anterior Cruciate Ligament Injury

Interventions

Type	Name	Description
PROCEDURE	Surgically treatment of the ACL	Surgical initial ACL treatment
OTHER	Non surgical initial ACL treatment	Non surgical initial ACL treatment

Timeline

• Start date: 2017-06-09
• Primary completion: 2017-12-31
• Completion: 2018-06-30
• First posted: 2017-06-09
• Last updated: 2017-07-02

Locations

1 site across 1 country: Sweden