| Not Yet Recruiting | Outpatient Floor Pedal Bike Utilization NCT06586190 | Wake Forest University Health Sciences | N/A |
| Not Yet Recruiting | Resurfacing of Foot and Distal Leg Soft Tissue Defects Using Reversed Pedicled Peroneal Artery Flaps Augmented NCT07453199 | Assiut University | N/A |
| Enrolling By Invitation | Neurophysiology of Ankle Instability NCT06576687 | University of Nebraska | N/A |
| Not Yet Recruiting | The Applicability of the Cumberland Ankle Instability Tool in Basketball Athletes. NCT06927557 | Hacettepe University | — |
| Completed | Impact of Hyperarch Fascia Training on Ankle Health and Exercise Performance NCT06959472 | Applied Science & Performance Institute | N/A |
| Recruiting | Assessment of the Quality of Life of Patients Visiting the Emergency Department of the Saint-Brieuc Hospital F NCT07054892 | Centre Hospitalier de Saint-Brieuc | — |
| Completed | Balance Training With Progressive Intermittent Visual Occlusions in Chronic Ankle Instability(RCT) NCT07108491 | Sahmyook University | N/A |
| Recruiting | Kinesio Taping Effects on Balance and Ankle Proprioception NCT06832111 | University of Beykent | N/A |
| Recruiting | Spinal and Supraspinal Control in Chronic Ankle Instability NCT06898554 | Ayca Yagcioglu | N/A |
| Enrolling By Invitation | The Safety of Reusing Walking Boot Components for Patients Recovering From Acute Foot and Ankle Injuries NCT07287969 | University of Utah | N/A |
| Completed | Kinesiology Taping and Ankle Stability in Acute Injuries During Stair Descent NCT06936033 | Ningbo University | N/A |
| Recruiting | The Effect of Taping on Plantar Pressure Distribution in Players With Chronic Ankle Instability NCT06499935 | Cairo University | N/A |
| Recruiting | Does Performing a Composite Test 3 Months Post-operatively Reduce the Risk of Failure to Return to Sport After NCT06395714 | Clinique du Sport, Bordeaux Mérignac | N/A |
| Active Not Recruiting | JuggerKnot With Broadband PMCF Study NCT05762588 | Riverpoint Medical | — |
| Not Yet Recruiting | Functional Outcomes Following Ankle Fracture Fixation With or Without Ankle Arthroscopy NCT06086223 | Assiut University | N/A |
| Completed | Perineural Dexamethasone on the Duration of Popliteal Nerve Block for Anesthesia After Pediatric Ankle Surgery NCT06086418 | Poznan University of Medical Sciences | Phase 4 |
| Unknown | Diagnostic Ultrasonography in Physiotherapy NCT05916300 | Petr Routner | — |
| Completed | Effects of Progressive Exercise Method Using Balance Board in Recreational Athletes With Functional Ankle Inst NCT06041243 | Acibadem University | N/A |
| Completed | The Effect of Different Talocrural Joint Mobilization Techniques in Lateral Ankle Sprain NCT06295198 | Bahçeşehir University | N/A |
| Completed | Turkish Language and Cross-cultural Adaptation of the Cumberland Ankle Instability Tool NCT05977660 | Eskisehir Technical University | — |
| Terminated | Weight Change With Controlled Ankle Movement (CAM) Boot Use NCT05692401 | Nell Blake, DPM | N/A |
| Completed | Comparative Effects of Neuromuscular Training and Mobilization With Movement in Professional Athletes With Ank NCT06303141 | Riphah International University | N/A |
| Unknown | The Effects of Combined Neuro-vestibular-ocular Exercises and Myofascial Release on Proprioception and Perform NCT05799885 | Yeditepe University | N/A |
| Unknown | A Morphological Study in Volleyball Athletes With Cronic Ankle Instability NCT05746663 | Hacettepe University | — |
| Completed | The Effects of Open Versus Closed Kinetic Chain Exercises on Ankle Joint Function NCT05717426 | Sehat Medical Complex | N/A |
| Completed | Erector Spinae Plane Block and Ankle and Foot Surgery NCT05708742 | Fayoum University Hospital | N/A |
| Completed | Effects of Balance Training on Corticospinal Excitability in People With Chronic Ankle Instability NCT05655143 | Old Dominion University | N/A |
| Completed | Effect of Chronic Ankle Instability on Core Stabilization, Dynamic Balance and Agility NCT05441319 | Yeditepe University | — |
| Completed | Percussive Therapy Reduced EMG Activity During Calf Raise in Limbs With and Without Chronic Ankle Instability NCT06343207 | Charles University, Czech Republic | N/A |
| Completed | Analysis of Balance and Functional Hop Tests in Athletes With Lower Extremity Injuries by Dual Task Study NCT05484778 | Istanbul University | N/A |
| Completed | Translation and Reliability of FAAM-U NCT05997797 | University of Lahore | — |
| Completed | How is Calf Muscle Endurance Related to Ankle Injuries in TeamGym Athletes? NCT05323773 | Susanne Beischer | — |
| Completed | PRICE vs PEACE and LOVE in Adolescent Lateral Ankle Sprain Rehabilitation NCT07287020 | Lithuanian University of Health Sciences | N/A |
| Completed | Monster Screw System Post-Market Clinical Follow-Up Study NCT05190159 | Paragon 28 | — |
| Completed | Grappler Interference Screw Post-Market Collection of Patient Reported Outcome Measures NCT05190874 | Paragon 28 | — |
| Recruiting | Comparing Clinical Outcomes of Suture Button Versus Fibulink Fixation for Acute Ankle Syndesmosis Injuries NCT05729542 | University of California, San Diego | N/A |
| Active Not Recruiting | Ankle Instability Using Foot Intensive Rehabilitation NCT04493645 | Matthew Hoch | N/A |
| Completed | Weight Variations Impacts on the Ankle of the Child NCT05074511 | Delta University for Science and Technology | — |
| Terminated | Evaluation of Functional Outcomes at 2 Months According to Therapeutic Management, in Trauma With Low-grade Os NCT05009342 | University Hospital, Brest | N/A |
| Unknown | Sural Flap and Anterolateral Thigh Flap in Tissue Reconstruction Around the Ankle NCT04906967 | Sohag University | N/A |
| Completed | Grappler® Interference Screw Post-Market Clinical Follow-Up Study NCT04893824 | Paragon 28 | — |
| Completed | Turkish Version of the Ankle Instability Instrument NCT04816058 | Acibadem University | — |
| Completed | Neuromuscular Training vs Strength Training NCT05250739 | DAVID CRUZ DÍAZ | N/A |
| Completed | Italian Version of The Cumberland Ankle Instability Tool (CAIT) NCT04644601 | University of Bologna | — |
| Completed | Effects of Gait Retraining With Auditory Feedback NCT04302961 | University of North Carolina, Charlotte | EARLY_Phase 1 |
| Completed | Foam Rolling and Tissue Flossing of the Cuff Muscles NCT04367532 | Wroclaw University of Health and Sport Sciences | N/A |
| Completed | Ankle Trauma: an Emergency Nurse Assessment Study NCT04126837 | University Hospital, Grenoble | N/A |
| Completed | External Versus Internal Feedback in Patients With Chronic Ankle Instability NCT04131842 | University of North Carolina, Charlotte | N/A |
| Completed | Transcutaneous Oxygen Pressure of the Injured Ankle as Predictor of Postoperative Cutaneous Pain NCT04209582 | Nantes University Hospital | — |
| Completed | Effect of Ankle Taping and Bandaging on Balance and Proprioception Among Healthy Volunteers NCT04583059 | Istanbul Gelisim University | N/A |
| Unknown | Use of Sterile HemaClear Tourniquet Below Calf Versus Pneumatic Tourniquet at the Thigh for Ankle and Foot Sur NCT04818775 | Hospital do Coracao | N/A |
| Completed | Hydrotherapy With Hydrogen-rich Water vs. RICE Protocol Following Acute Ankle Sprain NCT04167202 | University of Novi Sad, Faculty of Sport and Physical Education | N/A |
| Completed | Deltoid Ligament Arthroscopic Repair in Ankle Fractures: Case Series NCT04473638 | Federal University of São Paulo | — |
| Completed | Early Prescription of Radiography Using the Ottawa Ankle Rules by a Nurse in the Management of Isolated Ankle NCT04021511 | Centre Hospitalier de Saint-Brieuc | N/A |
| Completed | Medial and Lateral Combined Ligament Arthroscopic Repair for Multidirectional Ankle Instability: Case Series NCT04459910 | Federal University of São Paulo | — |
| Unknown | Patient Education Using 3D Printed Model NCT04009252 | Ottawa Hospital Research Institute | N/A |
| Completed | The Effect of Visual Input in Athletes With Chronic Ankle Instability NCT03872973 | Hacettepe University | N/A |
| Completed | The Effects of Unilateral Balance Training Among Athletes With Chronic Ankle Instability NCT04139044 | Yeditepe University | N/A |
| Completed | Indications for Osteochondral Allograft Transplantation NCT03711747 | University of Missouri-Columbia | — |
| Unknown | Magnetic Resonance Imaging Evaluation of Lateral Ankle Instability NCT03695965 | Assiut University | — |
| Completed | Clinical Comparative Study of Personalized Shoulder, Knee and Ankle Brace NCT04936412 | Jia-kuo yu | N/A |
| Unknown | Effects of Gait Biofeedback and Impairment-based Rehabilitation in Individuals With Chronic Ankle Instability NCT03507803 | University of Virginia | Phase 3 |
| Completed | Ankle Instability Treatment in Patients With Chronic Ankle Instability NCT03189784 | University of Jaén | N/A |
| Completed | Video Aided Mindful Deep Breathing for Pain Management NCT04812158 | Universiti Tunku Abdul Rahman | N/A |
| Completed | The Evaluation of Ankle Joint Braces Efficiency NCT04586036 | Barbara Łysoń | N/A |
| Completed | Comparison of Screw and Suture Button Technique Results in Ankle Syndesmosis Injuries NCT05538845 | Ataturk University | — |
| Completed | Comparison of The Acute Effects of Different Stretching Methods on Ankle Joint Range In Healty Older Adults NCT05130372 | Hacettepe University | N/A |
| Completed | The Thrust Technique of Tibiotarsal Joint on the Symptomatology of Pain at Classical Ballet Dancers NCT04512651 | Universidade Estadual do PiauÍ | N/A |
| Unknown | Benchmarking the iOS Balance Application Against the Berg Balance Test NCT02705690 | Stannah Stairlifts | N/A |
| Unknown | Effects of Proprioceptive Training on Neurofunctional Control and Ankle Sprains Incidence NCT02739308 | Federal University of Rio Grande do Sul | N/A |
| Terminated | Investigation of Corticosteroid Versus Placebo Injection in Patients With Syndesmotic Ligament Injury or High NCT02892500 | Sanford Health | Phase 2 |
| Completed | Lateral Ankle Sprain and Platelet Rich Plasma NCT02609308 | Universidad Autonoma de Nuevo Leon | N/A |
| Unknown | MRI Appearance of Injured Ligament and Tendon of the Ankle in Different Postures NCT03049423 | The First Hospital of Hebei Medical University | — |
| Completed | Associated Joint Pain With Controlled Ankle Movement (CAM) Walker Boot Wear NCT03312933 | Brigham and Women's Hospital | — |
| Completed | Muscle Activation in Chronic Ankle Instability and the Effect of an Exercise Programme NCT02276339 | University College Dublin | N/A |
| Completed | Ankle Athletic Taping Fatigue After a Standard Tennis Warm up NCT02187406 | CEU San Pablo University | N/A |
| Unknown | Application of 3D Printing Technology in Subtalar Arthrodesis NCT03152916 | Southwest Hospital, China | N/A |
| Unknown | 3D Printed Guide in Ankle Arthrodesis NCT03626935 | Southwest Hospital, China | N/A |
| Terminated | Acupuncture for Pain Control in the Emergency Department NCT02013908 | Korean Medicine Hospital of Pusan National University | N/A |
| Completed | 5% Topical Ibuprofen (IBU) for Ankle Sprain NCT01945034 | Pfizer | Phase 3 |
| Unknown | A Powered Ankle Foot Rehabilitation Orthosis NCT01942772 | Beijing Institute of Technology | N/A |
| Completed | Triage-Based Application of OFAR on the Number of Radiographs Ordered NCT01779804 | Lehigh Valley Hospital | — |
| Completed | Comparison of Plaster of Paris Against Tubigrip for the Treatment of Lateral Ankle Sprains NCT01499966 | Liaquat National Hospital & Medical College | N/A |
| Unknown | A Prospective Study Comparing Different Clinical Decision Rules in Adult and Pediatric Ankle Trauma NCT01205841 | KU Leuven | N/A |
| Unknown | Early Weightbearing and Mobilization Versus Non-Weightbearing and Mobilization in Unstable Ankle Fractures NCT01196338 | University of Toronto | N/A |
| Completed | Alcohol Cessation Intervention in an Acute Surgical Setting NCT00986791 | Bispebjerg Hospital | N/A |
| Completed | Regular vs Intermittent Dose Ibuprofen for the Treatment of Ankle Sprains in Children NCT01092676 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Suspended | Lymphomyosot for Ankle Edema Following Fracture NCT00884988 | Shaare Zedek Medical Center | Phase 2 |
| Completed | Functional Treatment for Acute Ankle Sprains: Softcast Wrap Versus MOKcast NCT01586390 | Spaarne Gasthuis | Phase 2 |
| Completed | Medico Economic Evaluation of Dermal Substitute Integra® for Coverage of Inferior Limb Traumatic Skin Loss NCT00906672 | University Hospital, Bordeaux | Phase 3 |
| Completed | Intraoperative Three Dimensional Fluoroscopy Compared to Standard Fluoroscopy for the Assessment of Reduction NCT00556010 | Hadassah Medical Organization | — |
| Completed | Rest Easy: Is Bed Rest Really Necessary After Surgical Repair of an Ankle Fracture? NCT00690651 | The Alfred | N/A |
| Completed | A Multicenter Randomized Trial Comparing Antiglide and Lateral Plate Fixation in Ankle Fractures NCT00718302 | Boston Medical Center | N/A |
| Completed | Effects of Proximal and Distal Tibiofibular Joint Manipulation on Lower Extremity Muscle Activation, Ankle Ran NCT00601471 | University of Virginia | N/A |
| Completed | Effect of Neuromuscular Warm-up on Injuries in Female Athletes NCT01092286 | Ann & Robert H Lurie Children's Hospital of Chicago | N/A |
| Completed | Operative Versus Non Operative Treatment for Unstable Ankle Fractures NCT00336752 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Unknown | Clinical Use of Andante SmartStep System in Gait Rehabilitation NCT00268658 | Soroka University Medical Center | N/A |
| Terminated | Comparative Results of Conservatively and Surgically Treated Adolescents With Triplane and Juvenile Tillaux An NCT00541580 | Hadassah Medical Organization | — |