NCT07526636

Pattern And Outcome Of Neonatal Gastrointestinal Emergencies In Assiut University Children Hospital

Pattern And Outcome Of Neonatal Gastrointestinal Emergencies In Assiut University Children Hospital: A Prospective Observational Cohort Study

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 120 (estimated)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: 1 Minute – 28 Days
• Healthy volunteers: —

Summary

This prospective observational study aims to evaluate the pattern, clinical presentation, complications, and short-term outcomes of neonates admitted with gastrointestinal emergencies to the NICU at Assiut University Children Hospital. Data will be collected from admission through discharge, including demographic, antenatal, natal, clinical, nutritional, laboratory, and radiological information, to identify the most common emergencies and factors associated with adverse outcomes.

Detailed description

This prospective observational cohort study will be conducted at the Neonatal Intensive Care Unit (NICU) of Assiut University Children Hospital. The study aims to evaluate the pattern, clinical presentation, complications, and short-term outcomes of neonatal gastrointestinal emergencies. Eligible neonates will be enrolled consecutively from admission until discharge. Both term and preterm neonates will be included. Data will be systematically collected on demographic characteristics, antenatal and natal history, clinical presentation, feeding practices, laboratory investigations, and radiological findings. Management approaches, including medical and surgical interventions, will be documented. Patients will be followed throughout their hospital stay to assess outcomes, including recovery, complications, need for surgical intervention, and mortality. The study also aims to identify the most common types of gastrointestinal emergencies and determine the clinical and demographic factors associated with adverse outcomes among affected neonates.

Conditions

• Necrotizing Enterocolitis
• Intestinal Atresia
• Malrotation
• Hirschsprung Disease

Timeline

• Start date: 2026-05-01
• Primary completion: 2027-04-01
• Completion: 2027-04-01
• First posted: 2026-04-13
• Last updated: 2026-04-13