Trials / Not Yet Recruiting
Not Yet RecruitingNCT07470710
Study on the Application of ¹⁸F-FCOB04, a MAO-B Targeted PET Imaging Agent, in Neurodegenerative Diseases
- Status
- Not Yet Recruiting
- Phase
- EARLY_Phase 1
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- Sponsor
- Peking Union Medical College Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Accepted
Summary
In this clinical trial, we intend to perform 18F-FCOB04 PET imaging in patients with neurodegenerative diseases to observe the brain uptake of this tracer.We will investigate the distinct imaging patterns of brain MAO-B expression in patients with various neurodegenerative diseases.Correlation analysis will be conducted between imaging findings and relevant clinical indicators.This study aims to evaluate the role of 18F-FCOB04 in the auxiliary diagnosis of neurodegenerative diseases, as well as to assess the tolerability and safety of the tracer and the imaging procedure.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | 18F-FCOB04 | Single intravenous administration of the investigational PET radiotracer 18F-FCOB04 followed by PET/CT imaging for evaluation of safety, biodistribution, radiation dosimetry, and target-specific uptake. |
Timeline
- Start date
- 2026-03-09
- Primary completion
- 2026-12-31
- Completion
- 2026-12-31
- First posted
- 2026-03-13
- Last updated
- 2026-03-13
Source: ClinicalTrials.gov record NCT07470710. Inclusion in this directory is not an endorsement.