NCT07456475

Metaverse Applications in Clinical Neurorehabiliation: Device Feasibility

Tele-Rehabilitation Solutions With Innovative Cores of Extended Reality Based on Metaverse

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 25 (estimated)
• Sponsor: Istituto per la Ricerca e l'Innovazione Biomedica · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Accepted

Summary

The main objective of the TERSICORE project is the development of a new advanced set of exergames in the Metaverse that can be used in all clinical and home rehabilitation devices to improve the cognitive therapy of neurological patients by exploiting the potential of social rehabilitation. Five specific exargames will be developed: a) Cooking therapy (Coordinating in a kitchen to complete a dish through shared activities); b) Escape Room (Exiting a simulated room by solving problems and logic puzzles); c) Nostalgia Bits (Sharing personal reminiscence narratives within simulated spaces); d) NeuroTeam (Mindfulness); and e) Truman Show Exploration of an urban space and role-playing. All exargames will be validated on a small population of neurological patients according to cognitive profile.

Conditions

• Neurological Disorder
• Multiple Sclerosis
• Parkinson Disease
• Stroke
• Traumatic Brain Injury

Interventions

Type	Name	Description
DEVICE	Cognitive rehabilitation with TERSICORE digital platform	Small groups of end-users will participate in various cognitive tasks carried out in common virtual environments (Metaverse).

Timeline

• Start date: 2025-06-06
• Primary completion: 2027-04-01
• Completion: 2027-07-01
• First posted: 2026-03-06
• Last updated: 2026-03-06

Locations

1 site across 1 country: Italy