NCT07451197

Family-Focused Study to Support Medication for Opioid Use Disorder

Family-focused Digital Intervention for MOUD Initiation and Retention

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 338 (estimated)
• Sponsor: University of Wisconsin, Madison · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of this clinical trial is to develop and test whether a text- and web-based tool called FamilyCHESS - designed for individuals with opioid use disorder (OUD) and a concerned significant other (CSO) - can help the identified patient (IP) begin and stay on medication for opioid use disorder (MOUD).

Conditions

• Opioid Use Disorder
• Opioid Use Disorder, Moderate
• Opioid Use Disorder, Severe

Interventions

Type	Name	Description
BEHAVIORAL	FamilyCHESS	Participants will have access to the FamilyCHESS system on their personal smartphone. FamilyCHESS incorporates Invitation to Change (ITC), a combination of Community Reinforcement and Family Training (CRAFT), Acceptance and Commitment Therapy (ACT), and Motivational Interviewing (MI) training principles and components for a CSO (e.g., parent, spouse/romantic partner, adult child, other family member or friend) to encourage and support the patient to engage in treatment.
BEHAVIORAL	Standard of Care	Participants will receive links to Substance Abuse and Mental Health Services Administration (SAMHSA) resources for MOUD

Timeline

• Start date: 2027-07-01
• Primary completion: 2031-07-01
• Completion: 2031-07-01
• First posted: 2026-03-05
• Last updated: 2026-04-13

Locations

2 sites across 1 country: United States