NCT07440017

Older Age and Generalization

Effects of Older Age on the Neural Basis of Memory Generalization

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 360 (estimated)
• Sponsor: Caitlin Bowman · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical is to learn how the brain supports different kinds of memory decisions in healthy young and older adults. The main question it seeks to answer is: Do older adults make memory decisions by integrating across experiences? Young (aged 18-30 years) and older (aged 65-80 years) participants will complete a memory task while undergoing functional MRI to measure their brain responses. Researchers will compare brain measures of integration in older adults to those of young adults to see if integration increases in older age.

Conditions

• Aging

Interventions

Type	Name	Description
BEHAVIORAL	Memory decision type	Subjects will be probed to either remember an association they saw directly during the study phase or to make an inference across indirectly associated items.

Timeline

• Start date: 2026-06-01
• Primary completion: 2029-12-01
• Completion: 2029-12-31
• First posted: 2026-02-27
• Last updated: 2026-03-23

Locations

1 site across 1 country: United States