NCT07410871

Degenerative Spondylolisthesis Accompanying LSS: Do We Need Fusion?

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 52 (actual)
• Sponsor: Kafrelsheikh University · Academic / Other
• Sex: All
• Age: 50 Years
• Healthy volunteers: Not accepted

Summary

This study aimed to compare clinical results of decompression alone using minimal invasive unilateral laminotomy for bilateral decompression versus classical decompression and instrumentation and fusion.

Detailed description

The term "lumbar spinal stenosis" (LSS) describes the anatomical narrowing of the spinal canal, which occurs in older people because of spinal ageing. Initial treatment is usually medical. Surgical management is recommended for patients with failed non-surgical trials. As claudication is always the main complain, lumbar canal decompression is the traditional surgical treatment. Although adding instrumentation and fusion is not uncommon and widely used. In the literature, the benefit of fusion, is treating instability that causes degenerative spondylolisthesis, improve back pain if present, and avoid slippage progression, which possibly will occur with generous decompression and disruption of the posterior column.

Conditions

• Degenerative Spondylolisthesis
• Lumbar Spinal Stenosis
• Fusion

Interventions

Type	Name	Description
PROCEDURE	Unilateral laminotomy decompression	Patients underwent unilateral laminotomy decompression.
PROCEDURE	Decompression and fusion	Patients underwent a posterior decompression, (either with or without preservation of midline bands) was followed by instrumentation using pedicle screws with rods and intervertebral fusion device.

Timeline

• Start date: 2025-01-01
• Primary completion: 2025-06-29
• Completion: 2025-06-29
• First posted: 2026-02-13
• Last updated: 2026-02-13

Locations

1 site across 1 country: Egypt