| Not Yet Recruiting | Assessing Safety of Cervical Spine Fusion With NMP® NCT07245940 | Red Rock Regeneration Inc. | — |
| Withdrawn | Effect of RECK in Posterior Spinal Fusion NCT06447194 | University of Maryland, Baltimore | Phase 1 / Phase 2 |
| Recruiting | Restoring Segmental Lumbar Lordosis After Failed Previous Fusion at the Same Level NCT07050290 | N.N. Priorov National Medical Research Center of Traumatology and Orthopedics | N/A |
| Completed | Degenerative Spondylolisthesis Accompanying LSS: Do We Need Fusion? NCT07410871 | Kafrelsheikh University | — |
| Recruiting | Mid- or High-flex Rods Versus Low-flex Rods of SpineShape System IV for Treatment of Degenerative Lumbar Spine NCT06320899 | SpineSave AG | N/A |
| Recruiting | Effect of Degenerative Spondylolisthesis on the Clinical Outcome of Unilateral Biportal Endoscopy for Lumbar S NCT06394089 | Beijing Friendship Hospital | — |
| Enrolling By Invitation | Natural Matrix Protein™ (NMP™) Fibers in Cervical and Lumbar Interbody Fusion NCT06000319 | Induce Biologics USA Inc. | — |
| Recruiting | Short-term Clinical Outcome of Cortical Bone Trajectory Compared With the Traditional "Open" and Minimal Invas NCT05538416 | Jos M. A. Kuijlen | — |
| Completed | Clinical Evaluation of Orion Lamina Cover in Patients Undergoing Lumbar Laminectomy With Instrumented Fusion NCT06532968 | Orion Biotech Inc. | N/A |
| Recruiting | Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery NCT05029726 | John O'Toole | Phase 4 |
| Completed | TLIF Osteo3 ZP Putty Study (Also Known as the TOP Fusion Study) NCT05114135 | OssDsign | N/A |
| Completed | Instability in the Lumbar Spine of Patients With Age Related Changes and Narrowing of the Spinal Canal (Spinal NCT04406987 | Spine Centre of Southern Denmark | — |
| Completed | XLIF Decade Plate System Study NCT04689880 | NuVasive | — |
| Completed | Re-operation Rates of Concorde Bullet Device Versus Conduit Titanium Interbody Graft for Lumbar Fusion NCT05993195 | Lahey Clinic | — |
| Terminated | Methadone for Spinal Fusion Surgery. NCT04764825 | University of Aarhus | Phase 4 |
| Completed | Clinical Decision-Making and Virtual Reality Exercise NCT05375201 | National Taiwan University Hospital | N/A |
| Terminated | First-In-Human Study of AK1320 Encapsulated Microspheres (AK1320 MS) NCT04483297 | Asahi Kasei Therapeutics Corporation | Phase 1 |
| Enrolling By Invitation | Lumbar Interbody Implant Study NCT04418830 | NuVasive | — |
| Unknown | Safety Evaluation of ART352-L in Subjects Undergoing Posterolateral Spinal Fusion NCT04378543 | Ankasa Regenerative Therapeutics, Inc. | Phase 1 / Phase 2 |
| Withdrawn | The Efficacy of Continuous Cold-Therapy on Postoperative Pain and Narcotics Use Following Spinal Fusion NCT03640338 | Rush University Medical Center | N/A |
| Completed | Modulus in XLIF Study NCT04418817 | NuVasive | — |
| Completed | Fibergraft Interbody Fusion Retrospective NCT03898232 | Bone and Joint Clinic of Baton Rouge | — |
| Completed | Clinical Outcomes Associated With the Use of ViviGen® for the Treatment of Lumbar Degenerative Disc Disease NCT03733626 | Corewell Health East | N/A |
| Active Not Recruiting | SLIP II Registry: Spinal Laminectomy Versus Instrumented Pedicle Screw Fusion NCT03570801 | Lahey Clinic | N/A |
| Completed | The Five-repetition Sit-to-stand Test for Lower Back Pain or Radiculopathy NCT03303300 | Marc Schröder | — |
| Withdrawn | Efficacy of Using Solum IV and BMC With GFC in TLIF NCT03223701 | Seton Healthcare Family | Phase 4 |
| Completed | A Pivotal Study of the Premia Spine TOPS™ System NCT03012776 | Premia Spine | N/A |
| Active Not Recruiting | LimiFlex Clinical Trial for the Treatment of Degenerative Spondylolisthesis With Spinal Stenosis NCT03115983 | Empirical Spine, Inc. | N/A |
| Unknown | Unilateral Versus Bilateral TLIF for Degenerative Lumbar Spondylolisthesis NCT03856554 | Kyungpook National University Hospital | N/A |
| Withdrawn | "Is Instrumentation Necessary for "Static" Degenerative Spondylolisthesis" NCT02530775 | University of Pittsburgh | N/A |
| Completed | Lumbar Stabilization Exercises vs Flexor Exercises in Degenerative Spondylolisthesis NCT02664688 | Instituto Nacional de Rehabilitacion | N/A |
| Completed | Lumbar Fusion With The Icotec CF/PEEK Pedicle System In Combination With The Icotec CF/PEEK TLIF Cage ETurn™ NCT02087267 | Sitona AG | — |
| Active Not Recruiting | The NORDSTEN Studies/The Observational Cohort Study NCT03562936 | Haukeland University Hospital | — |
| Unknown | Interbody vs Instrumented Posterolateral Fusion Following Decompression for Lumbar Spinal Stenosis With Degene NCT01921530 | The London Spine Centre | Phase 4 |
| Terminated | Dynesys Spinal System Post Market 522 Study NCT01528072 | Zimmer Biomet | N/A |
| Completed | Valeo OL Interbody Fusion Devices for Posterior Lumbar Interbody Fusion SNAP Trial NCT01557829 | Amedica Corporation | N/A |
| Completed | Safety and Preliminary Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discecto NCT01097486 | Mesoblast, Ltd. | Phase 2 |
| Completed | Safety and Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy and Fusio NCT01106417 | Mesoblast, Ltd. | Phase 1 / Phase 2 |
| Completed | Safety and Preliminary Efficacy Study of NeoFuse in Subjects Requiring Lumbar Interbody Fusion NCT00996073 | Mesoblast, Ltd. | Phase 2 |
| Completed | SPONGIT: Comparison of Two Surgical Approaches in the Treatment of Degenerative Spondylolysthesis NCT00869882 | University Hospital, Bordeaux | N/A |
| Withdrawn | Safety and Efficacy Study of NeoFuse in Subjects Requiring Posterolateral Lumbar Fusion NCT00810212 | Mesoblast, Ltd. | Phase 1 / Phase 2 |
| Completed | Multimodal Perioperative Pain Management NCT01513564 | Northern Orthopaedic Division, Denmark | N/A |
| Completed | Evaluation Of Spinelink® Fixation In The Treatment Of Degenerative Spondylolisthesis And Spinal Instability NCT00726310 | Zimmer Biomet | — |