NCT07401069

Homemade Herbal Mouthwash in Gingivitis. A Randomized Clinical Trial.

The Effect of Homemade Herbal Mouthwash Versus Chlorhexidine on Plaque Accumulation in Gingivitis. A Randomized Clinical Trial.

• Status: Not Yet Recruiting
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 12 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

Gingivitis is a very common oral disease that may progress to the more destructive periodontitis if not treated. As oral plaque is a key player in gingivitis, plaque control by professional scaling and oral hygiene measures represents the main line of treatment. Among the oral hygiene measures, using chlorhexidine mouthwash is considered the gold standard in mouthwashes. However, due to its side effects, a safer and more acceptable mouthwash is needed. Therefore, this study proposes mouthwashes made of infusion of natural herbs as an alternative.

Conditions

• Gingivitis

Interventions

Type	Name	Description
DRUG	Chlorhexidine 0,12%	chlorhexidine 0.12% mouthwash twice daily for 7 days
DRUG	herbal Mouthwash	Mouthwash made at home by boiling herbs in water and then saving the solution in a tightly closed container for daily use for 7 days

Timeline

• Start date: 2026-02-01
• Primary completion: 2026-06-30
• Completion: 2026-07-30
• First posted: 2026-02-10
• Last updated: 2026-02-10