NCT07390305

Multidimensional Correlation Study on Skin Aging in Menopausal Women

Study on the Correlation Between Skin Aging in Exposed / Non Exposed Areas and Menopausal Symptoms, Emotions, and Sleep in Menopausal Women

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 100 (actual)
• Sponsor: ChinaNorm · Industry
• Sex: Female
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Primary Objective: This study primarily aims to compare skin aging characteristics between women at different stages of reproductive aging in both sun-exposed and non-exposed areas, based on skin indicators collected during a single laboratory visit. Furthermore, through a 30-day at-home tracking period (for the late-stage and postmenopausal groups) or one menstrual cycle (for the early-stage and young group), we seek to analyze the temporal dynamics of changes in skin condition, mood, sleep quality, and menopausal hot flashes. Secondary Objective: The secondary objective is to examine differences in skin conditions across life stages by recruiting mother-daughter pairs (where the young group consists of the biological daughters of the late-stage and postmenopausal groups). The core focus is to leverage shared genetic backgrounds to explore how skin characteristics, particularly in different body areas, may change over time or in response to hormonal fluctuations. By comparing these characteristics across age groups, this study seeks to identify key variation patterns and their contributing factors, thereby laying the groundwork for further mechanistic investigations and practical applications.

Conditions

• Skin Aging
• Reproductive Aging
• Menopause
• Genetic Factors

Timeline

• Start date: 2025-11-11
• Primary completion: 2026-01-20
• Completion: 2026-01-20
• First posted: 2026-02-05
• Last updated: 2026-02-05

Locations

1 site across 1 country: China