Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT07375212

VAPorized Administration of Bumetanide for Outpatient Relief in Heart Failure

Acute Hemodynamic and Blood Volume Effects of Single-Dose Intranasal Bumetanide in Patients Implanted With the CardioMEMS™ and Cordella™ HF Systems: a 24-Hour Prospective Pilot Study

Status
Withdrawn
Phase
Phase 4
Study type
Interventional
Enrollment
0 (actual)
Sponsor
Prisma Health-Upstate · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This trial is seeking to determine whether a single 4mg intranasal dose of bumetanide acutely reduces pulmonary artery pressure and blood volume in the outpatient setting for patients with heart failure and an implanted device for remote patient monitoring (i.e. Cordella or CardioMEMS).

Conditions

Interventions

TypeNameDescription
DRUGBumetanide, intranasal 4mgIntranasal route of administration for 4mg of bumetanide

Timeline

Start date
2026-01-21
Primary completion
2026-01-21
Completion
2026-01-21
First posted
2026-01-29
Last updated
2026-01-29

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT07375212. Inclusion in this directory is not an endorsement.