NCT07371390

Minimal Sedation During Knee Replacement Surgery

Minimal Sedation During Total Knee Arthroplasty: A Prospective Randomized Control Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study will test the use of active noise cancelling headphones with music or a movie during knee replacement surgery. Feedback from the surgical team and from patients regarding the headset system will be gathered to see if using it can reduce the amount of sedation needed during knee replacement procedures that use localized anesthesia.

Conditions

• Total Knee Arthroplasty

Interventions

Type	Name	Description
DEVICE	Active Noise Cancelling Headset System	The ANC Headset will allow patients to select music or a movie for audiovisual distraction during their surgery. This can be used when patients are not receiving general anesthesia (full sedation) for their surgery.

Timeline

• Start date: 2025-12-11
• Primary completion: 2026-11-24
• Completion: 2027-05-01
• First posted: 2026-01-27
• Last updated: 2026-01-27

Locations

1 site across 1 country: United States