NCT07362537

Enteral Nutrition Delivery in Prone Position Ventilated Patients With Moderate to Severe ARDS

Enteral Nutrition Delivery in Prone Position Ventilated Patients With Moderate to Severe Acute Respiratory Distress Syndrome: a Randomized Controlled Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Southeast University, China · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

This pilot study is aimed to compare and assess the impact, safety, and practical utility of gastric versus postpyloric feeding in moderate to severe ARDS patients with prone position ventilation. Patients included will be randomly assigned to receive enteral nutrition either through a nasogastric tube or a nasojejunal tube. The primary endpoint is the achievement of enteral nutrition goals. Secondary endpoints include the incidence of hospital-acquired infections, the number of ventilator-free days within 28 days, ICU length of stay, ICU mortality, 28-day mortality, 60-day mortality rates, the incidence of enteral nutrition intolerance, and the rate of enteral nutrition intake.

Conditions

• ARDS

Interventions

Type	Name	Description
PROCEDURE	enteral nutrition through nasojejunal tube	place nasojejunal tube for enteral nutrition
PROCEDURE	enteral nutrition through nasogastric tube	place nasogastric tube for enteral nutrition

Timeline

• Start date: 2026-01-20
• Primary completion: 2026-10-31
• Completion: 2026-10-31
• First posted: 2026-01-23
• Last updated: 2026-01-23

Locations

1 site across 1 country: China