NCT07361575

Study Comparing the Quality of Colon Cleanliness With Prepackaged LRD (Low-residue Diet) vs. Guided (POG).

A Single-blind, Randomized Study Comparing the Quality of Colon Cleanliness With Prepackaged LRD (Low-residue Diet) vs. Guided (POG).

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 230 (estimated)
• Sponsor: Clinique Paris-Bercy · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Low-residue diet (LRD) in patient improves the quality of the colon cleanliness and thus the adenoma detection rate (ADR). This is a key criterion in colonoscopy screening for colorectal cancer (CRC). The benefit of an LRD lasting more than 24 hours before colonoscopy has not been demonstrated compared to a 24-hour LRD. Few studies have evaluated the benefit of a prepackaged 24-hour LRD compared to simply receiving oral and written LRD instructions during a consultation. The aim of the study is to evaluate the usefulness of a prepackaged LRD (Colobox®) compared to simple LRD instructions on colon cleanliness (Boston score) in patients examined by endoscopy.

Conditions

• Colorectal Cancer Prevention
• Colorectal Cancer (Diagnosis)
• Colorectal Adenocarcinoma

Interventions

Type	Name	Description
PROCEDURE	Colonoscopy	Colonoscopy performed and Boston score evaluated
OTHER	Questionnaires	LRD satisfaction questionnaire LRD compliance questionnaire
OTHER	Pre-colonoscopy diet according to the investigator's oral instructions	24 hours before the colonoscopy, The patients follow a special diet, either by themselves according to the investigator's oral instructions
OTHER	Pre-colonoscopy diet by following a special preparation, Colobox.	24 hours before the colonoscopy, The patients follow a special diet, by following a special preparation, Colobox.

Timeline

• Start date: 2026-01-30
• Primary completion: 2026-11-15
• Completion: 2026-11-30
• First posted: 2026-01-23
• Last updated: 2026-02-17

Locations

1 site across 1 country: France