NCT07337876

Organ Preservation in Rectal Cancer by Dose Escalated MR Guided Adaptive Radiotherapy

• Status: Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: University Hospital Tuebingen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study is testing whether radiation delivered with MRI guidance using a so-called MR-linac in distal rectal cancer can result in a high rate of organ preservation. Patients will receive radiotherapy together with standard chemotherapy.

Conditions

• Rectal Cancer

Interventions

Type	Name	Description
RADIATION	Dose escalated radiotherapy using a 1.5 T MR-Linac	Dose escalated radiotherapy using a 1.5 T MR-Linac is given to the primary tumor and affected lymph nodes in an online adaptive manner

Timeline

• Start date: 2026-01-07
• Primary completion: 2029-01-01
• Completion: 2029-01-01
• First posted: 2026-01-13
• Last updated: 2026-02-17

Locations

1 site across 1 country: Germany