NCT07334392

Impact of a Multicomponent Exercise Program on Cognitive and Functional Outcomes in Patients With Mild Cognitive Impairment

Effectiveness of an Innovative Therapeutic Exercise Program on Physical and Cognitive Function in Mild Cognitive Impairment Due to Alzheimer's Disease

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 45 (estimated)
• Sponsor: University of Patras · Academic / Other
• Sex: All
• Age: 50 Years
• Healthy volunteers: Not accepted

Summary

The goal of this randomised clinical trial is to investigate the effectiveness of an innovative therapeutic exercise program emphasizing in dual-task exercises in people with amnestic Mild Cognitive Impairment. The main questions it aims to answer are: Does the innovative therapeutic exercise program improve gait and balance? Does the innovative therapeutic exercise program improve cognition? Researchers will compare the innovative therapeutic exercise program emphasizing in dual-task exercises to a therapeutic exercise program without emphasizing in dual-task exercises and to a control group (given instruction about the benefits of exercise). Participants will: * Perform the exercise program twice a week for three months. * Will be assessed before and after the intervention. * Will record The Borg Scale of Perceived Exertion every second week to monitor and assess the progression of exercise intensity.

Conditions

• Mild Cognitive Impairment
• Walking
• Balance
• Cognition

Interventions

Type	Name	Description
OTHER	Innovative therapeutic exercise program	Aerobic, strengthening and balance exercises combined with cognitive training -name: Experimental group 1 (EXP1)
OTHER	Therapeutic exercise program	Aerobic, strengthening and balance exercises without cognitive training- name: Experimental group 2 (EXP2)
OTHER	Flyer	The control group will receive only educational material in the form of a flyer, outlining the importance and potential benefits of physical activity, along with general lifestyle recommendations, without participating in the structured exercise intervention- name: Control group (CG)

Timeline

• Start date: 2025-12-01
• Primary completion: 2026-08-30
• Completion: 2026-11-30
• First posted: 2026-01-12
• Last updated: 2026-01-12

Locations

1 site across 1 country: Greece