NCT07310732

Clinical and Radiographic Assessment of Efficacy of Modified Minimally Invasive SurgicalTechnique (M-MIST) Alone and Combined With Enamel Matrix Proteins and Ox-derived Bone Graft in the Treatment of Single Bone Defects Between Teeth.

Clinical and Tomographic Efficacy of the Modified Minimally Invasive Surgical Technique (M-MIST) Alone and Combined With Enamel Matrix Derivative (EMD) and Bone Mineral Derived Xenograft (BMDX), in the Treatment of Isolated, Inter-dental Intra-bony Defects

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 45 (actual)
• Sponsor: Rungta College of Dental Sciences and Research · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study was performed to investigate the adjunctive clinical benefit of the application of enamel matric derivatives and xenograft with the modified minimally invasive surgical technique in the treatment of isolated intrabony defects in periodontally compromised subjects.

Conditions

• Periodontal Diseases
• Periodontal Bone Loss

Interventions

Type	Name	Description
PROCEDURE	modified minimally invasive surgical technique	modified minimally invasive surgical technique alone in interdental area
PROCEDURE	modified minimally invasive surgical technique plus emdogain	modified minimally invasive surgical technique with application of enamel matrix proteins in interdental area
PROCEDURE	modified minimally invasive surgical technique plus emdogain and xenograft	modified minimally invasive surgical technique with application of enamel matrix proteins and placement of bovine bone graft in interdental area

Timeline

• Start date: 2022-03-01
• Primary completion: 2024-09-01
• Completion: 2025-03-01
• First posted: 2025-12-30
• Last updated: 2025-12-30

Locations

1 site across 1 country: India