NCT07295093

Menopause Age and Anxiety-Depression

Association Between Age at Menopause and Levels of Anxiety and Depression

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 136 (actual)
• Sponsor: Ankara City Hospital Bilkent · Academic / Other
• Sex: Female
• Age: 24 Years
• Healthy volunteers: Accepted

Summary

Menopause is defined as the permanent cessation of menstrual cycles due to ovarian follicle depletion, typically occurring after age 50, and is associated with decreased estrogen levels. Primary ovarian insufficiency (POI) involves early ovarian dysfunction before age 40, with infertility as a key concern. Both menopause and POI may contribute to psychological symptoms, including anxiety and depression, influenced by sociodemographic and health factors. While literature reports anxiety in middle-aged women, data on its association with menopausal timing are limited. This study aims to compare women with POI and those undergoing natural menopause after age 40, assessing the relationship between age at menopause, anxiety, and depression, as well as the impact of fertility expectations on psychological well-being in POI patients.

Conditions

• Menopause
• Primary Ovarian Insufficiency (Poi)
• Anxiety
• Depression
• Menopausal Depression

Interventions

Type	Name	Description
OTHER	Beck Anxıety Inventory (BAI)	Beck Anxıety Inventory (BAI) Description: The scale will be self-administered and completed by the patient during the routine outpatient clinic visit.
OTHER	State-Trait Anxiety Scale (STAI) 1-2	State-Trait Anxiety Scale (STAI) 1-2 Description: The scale will be self-administered and completed by the patient during the routine outpatient clinic visit.

Timeline

• Start date: 2024-12-15
• Primary completion: 2025-08-05
• Completion: 2025-09-15
• First posted: 2025-12-19
• Last updated: 2025-12-19

Locations

1 site across 1 country: Turkey (Türkiye)