Trials / Recruiting
RecruitingNCT07279740
Combined Brain Stimulation and Methylphenidate Treatment for Apathy in Dementia
Methylphenidate Primed iTBS for Apathy in Neurocognitive Disorders
- Status
- Recruiting
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 12 (estimated)
- Sponsor
- Sunnybrook Health Sciences Centre · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
This study evaluates whether the combined treatment of methylphenidate and non-invasive brain stimulation, called intermittent theta burst stimulation, can effectively treat apathy in individuals with Alzheimer's disease or mixed AD/vascular dementia
Conditions
- Alzheimer s Disease
- Alzheimer Dementia (AD)
- Alzheimer Dementia
- Alzheimer Disease
- Apathy
- Apathy in Dementia
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | intermittent theta burst stimulation (iTBS) | iTBS is a form of repetitive transcranial magnetic simulation (rTMS), a non-invasive form of brain stimulation. |
| DRUG | Methylphenidate (MPH) | Participants will be on methylphenidate clinically prior to the trial |
Timeline
- Start date
- 2026-01-01
- Primary completion
- 2027-10-01
- Completion
- 2027-10-01
- First posted
- 2025-12-12
- Last updated
- 2025-12-12
Locations
1 site across 1 country: Canada
Source: ClinicalTrials.gov record NCT07279740. Inclusion in this directory is not an endorsement.