NCT07273526

Adrenaline V/s Dopamine in Fuid Refractory Septic Shock

Comparison of the Efficacy of Renaline and Dopamine in the Treatment of Fluid Refractory Septic Shock in Children

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 90 (estimated)
• Sponsor: Laiba Qamar · Academic / Other
• Sex: All
• Age: 1 Month – 12 Months
• Healthy volunteers: Not accepted

Summary

This study compares the efficacy of two drugs i.e Adrenaline and dopamine in fluid refractory type of septic shock which is a dreadful medical condition especially in children. The efficacy will be checked based on heart rate , GCS, capillary refill time , palpable pripheral pulse , urine output and systolic blood pressure.

Detailed description

This is a randomized control trial in which children / patients diagnosed with Fluid refractory Septic shock will be provided with one of the two drugs ina randomzied way and their efficacy will be assesed on the basis of correction of various parameters at various points of time.

Conditions

• Fluid Refractory Septic Shock
• Septic Shock

Interventions

Type	Name	Description
DRUG	Adrenaline	The adrenaline will be given as a vasoconstrictor in the dose of 0.1-0.3ug/kg/min to the patients in group A when diagnosed with fluid refractory septic shock
DRUG	Dopamine	The drug dopamine will be adminitered in dose of 10-20ug/kg/min to the patients of group B when diagnosed with fluid refractory septic shock.

Timeline

• Start date: 2025-06-01
• Primary completion: 2025-12-31
• Completion: 2025-12-31
• First posted: 2025-12-09
• Last updated: 2025-12-09

Locations

1 site across 1 country: Pakistan