Clinical Trials Directory

Trials / Not Yet Recruiting

Not Yet RecruitingNCT07270562

ORbital Atherectomy for Lesion Preparation in Patients With Chronic Limb-threatening ischEmia

Status
Not Yet Recruiting
Phase
Study type
Observational
Enrollment
250 (estimated)
Sponsor
Cardiovascular and Interventional Radiological Society of Europe · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

ORACLE is a Europe-wide study that will follow 250 people with critical limb-threatening ischemia (CLTI). It aims to see how well orbital atherectomy (OA) works in real-life practice. OA is a procedure that uses a tiny spinning tool to gently remove hard calcium from inside an artery, helping to open the vessel so other treatments-like balloons or stents-can work better. The study focuses on people who have heavily calcified arteries in the femoropopliteal or infrapopliteal areas of the leg.

Conditions

Interventions

TypeNameDescription
DEVICEStealth 360™ Peripheral Orbital Atherectomy System from AbbottThe Stealth 360™ Peripheral Orbital Atherectomy System uses a diamond-coated, eccentrically mounted crown with bi-directional capabilities that treat a wide range of vessels, enabling single device treatment of multiple lesions and vessel sizes.

Timeline

Start date
2026-04-01
Primary completion
2031-04-01
Completion
2031-12-01
First posted
2025-12-08
Last updated
2026-01-02

Source: ClinicalTrials.gov record NCT07270562. Inclusion in this directory is not an endorsement.