NCT07243353

Examination of the Effect of Nd:YAG Laser on Oxidative Stress and Matrix Metalloproteinase-9 in Teeth With Apical Periodontitis

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 58 (actual)
• Sponsor: Kırıkkale University · Academic / Other
• Sex: All
• Age: 25 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

The objective of this clinical investigation is to examine the impact of Nd:YAG laser therapy on oxidative stress and matrix metalloproteinase-9 (MMP-9) levels in teeth afflicted with apical periodontitis. Samples were collected from patients who had undergone treatment with the Nd:YAG laser and compared with samples collected from patients who had not received this treatment. The study commenced with a sample of 60 patients. However, the study was completed with 58 patients. The study concluded with the following finding: the use of Nd:YAG lasers was not found to be superior.

Conditions

• Apical Periodontitis
• Oxidative Stress

Timeline

• Start date: 2024-02-01
• Primary completion: 2024-11-01
• Completion: 2024-11-08
• First posted: 2025-11-21
• Last updated: 2025-12-15

Locations

1 site across 1 country: Turkey (Türkiye)