NCT07237438

TIVA Versus Balanced Anesthesia on Muscle Mass in CRC Surgery

Total Intravenous Anesthesia Versus Balanced Anesthesia on Loss of Muscle Mass After Colorectal Cancer Surgery

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Grigore T. Popa University of Medicine and Pharmacy · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study is aimed at clarifying changes in body composition during the perioperative period and identifying risk factors for skeletal muscle mass loss in patients with colorectal cancer. The investigators will asess the impact of the type of anaesthesia (total intravenous anaesthesia/sevoflurane anaesthesia) for colorectal surgery on the muscle function and mass, which will be evaluated using ultrasound, dynamometry and bioimpedance.

Conditions

• Colorectal Cancer (CRC)
• Sarcopenia

Interventions

Type	Name	Description
PROCEDURE	total intravenous anaesthesia	evaluate the impact of the type of anaesthesia (total intravenous anaesthesia (TIVA)/sevoflurane anaesthesia) for colorectal surgery on the muscle function and mass
PROCEDURE	sevoflurane anaesthesia	evaluate the impact of the type of anaesthesia (total intravenous anaesthesia (TIVA)/sevoflurane anaesthesia) for colorectal surgery on the muscle function and mass

Timeline

• Start date: 2025-09-20
• Primary completion: 2026-02-01
• Completion: 2026-06-01
• First posted: 2025-11-19
• Last updated: 2025-11-19

Locations

1 site across 1 country: Romania