NCT07197151

CYFIP1 and PKM2 Synergistically Regulate ROS and Glycolysis in Colorectal Cancer Through the AKT/mTOR/HIF-1α Cascad

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 32 (actual)
• Sponsor: hui hou · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Collect some tumor tissue specimens from patients who have undergone colorectal cancer surgery and conduct experiments such as immunohistochemistry to observe the expression of related genes in colorectal cancer.

Detailed description

We need to collect postoperative specimens and adjacent normal tissue specimens from patients with colorectal cancer for immunohistochemical staining. There is no need to conduct any other grouping of the patients.

Conditions

• Colorectal Cancer (CRC)
• Specimens Are to be Collected From Subjects Who Are Having or Have Had a Fluid or Tissue Removed, a Biopsy or a Blood or Bone Marrow Draw

Interventions

Type	Name	Description
OTHER	Perform surgery on patients with colorectal cancer and collect cancer and adjacent tissue specimens	Perform surgery on patients with colorectal cancer and collect cancer and adjacent tissue specimens

Timeline

• Start date: 2022-08-01
• Primary completion: 2025-09-01
• Completion: 2025-09-01
• First posted: 2025-09-29
• Last updated: 2025-09-29

Locations

1 site across 1 country: China