NCT07171918

Prospective Observational Study to Compare REMS vs NEWS2 for Patients Presenting to the ED With Sepsis

Prospective Observational Study to Determine the Utility of REMS in Comparison to NEWS2 for Predicting Morbidity and Mortality Among Patients Presenting to the ED Suspicion of Sepsis

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 130 (actual)
• Sponsor: Jubilee Mission Medical College and Research Institute · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Prospective observational study to determine the utility of Rapid Emergency Medicine Score (REMS) in comparison to National Early Warning Score2 (NEWS2) for predicting morbidity and mortality among patients presenting to the Emergency Department with clinical suspicion of Sepsis

Detailed description

Rapid Emergency Medicine Score (REMS) is an attenuated version of the Acute Physiology and Chronic Health Evaluation (APACHE) II score and has utility in predicting mortality in non- surgical patients. The NEWS2 can be used on all hospitalized patients to allow for the early detection of clinical deterioration and potential need for higher level of care. NEWS2 is closely associated with sepsis, however REMS is not so. But in recent studies comparing other EWS (Early Warning Scores) of sepsis, REMS was found to be superior. Hence comparing REMs against NEWS2 to determine prognostication value of both scores in sepsis.

Conditions

• Sepsis

Interventions

Type	Name	Description
DRUG	Antibiotics, Vasopressors	Both groups are scored on REMS and NEWS2, and then observed closely for the period of hospital stay with regard to ICU stay duration, ventilator days, vasopressor dependent days and total hospital duration

Timeline

• Start date: 2023-01-01
• Primary completion: 2024-06-30
• Completion: 2024-12-31
• First posted: 2025-09-15
• Last updated: 2025-09-15

Locations

1 site across 1 country: India