NCT07171346

Post Operative Use of Neuromuscular Electrical Stimulation (NMES) Device for ACLR Patients

Effects on Patient Outcomes With Post-Operative Use of Zynex Neuromuscular Electrical Stimulation (NMES): Zynex-25

• Status: Enrolling By Invitation
• Phase: N/A
• Study type: Interventional
• Enrollment: 25 (estimated)
• Sponsor: University of Kansas Medical Center · Academic / Other
• Sex: All
• Age: 15 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

This study is being conducted to learn about how neuromuscular electrical stimulation (NMES) in addition to standard of care aids in the recovery of muscle strength in patients undergoing ACLR procedure.

Detailed description

The addition of neuromuscular electrical stimulation (NMES) to standard ACLR rehabilitation has been demonstrated to improve knee extension and flexion compared to standard treatment only. NMES has also shown improved lower limb loading symmetry, walking velocity, stance time, cadence, maximum voluntary isometric contraction, motor unit behavior, muscle quality, and an increase in absolute muscle strength in functional tests compared to standard care of ACLR recovery. In this study we will be comparing bi-lateral presurgical and post surgical muscle strength symmetry in patients that follow the standard ACLR rehabilitation program and patients that use the NMES in addition to standard rehab.

Conditions

• ACL Reconstruction
• ACL Surgery
• ACL Injury
• Electrotherapy
• Muscle Atrophy or Weakness

Interventions

Type	Name	Description
DEVICE	Zynex NexWave Electrotherapy Device	All participants will use the NMES device in addition to standard rehabilitation

Timeline

• Start date: 2026-02-10
• Primary completion: 2027-11-01
• Completion: 2028-06-01
• First posted: 2025-09-12
• Last updated: 2026-03-17

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study