NCT07167225

Carcinogen and Toxicant Exposure Among Young Adults Who Co-Use E-cigarettes and Cannabis (Co-Tox Study)

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 150 (estimated)
• Sponsor: Roswell Park Cancer Institute · Academic / Other
• Sex: All
• Age: 18 Years – 25 Years
• Healthy volunteers: Accepted

Summary

This study evaluates the amount of nicotine, cannabis, and toxicants linked to the use of nicotine e-cigarette and/or cannabis products in the blood and urine of young adult users as well as the cannabis and nicotine use behaviors of consumers.

Detailed description

PRIMARY OBJECTIVE: I. To evaluate differences in self-reported nicotine and cannabis use behaviors and biomarkers of exposure to toxicants and carcinogens by product use status, to generate effect sizes required to calculate sample sizes needed for a larger study.

Conditions

• Cigarette Smoking-Related Carcinoma
• E-Cig Use

Interventions

Type	Name	Description
OTHER	Effectiveness of different recruitment approaches	Subjects will asked which type of recruitment material they've seen when completing the screening survey
OTHER	Choice of study completion locations	subjects will choose location when coordinator calls to schedule appointment
OTHER	Cannabis Engagement Assessment	Self reported measure of current cannabis use that contains 30 questions assessing quantity, frequency of use and method of consumption in the past 30 days.
OTHER	E-cigarette dependence Scale	A 22-item questionnaire measuring e-cigarette dependence. Higher scores indicate greater dependence.

Timeline

• Start date: 2025-04-03
• Primary completion: 2028-09-01
• Completion: 2028-09-01
• First posted: 2025-09-11
• Last updated: 2025-10-03

Locations

1 site across 1 country: United States