NCT07155330

High-flow Nasal Cannula Oxygenation in Sedated Endoscopy for High-risk Obstructive Sleep Apnea Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Zhejiang University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Hypoxia is the most common adverse event during propofol sedation for gastrointestinal endoscopy. The STOP-BANG questionnaire is a widely used, simple assessment tool for screening obstructive sleep apnea (OSA) risk. A STOP-Bang score ≥5 indicates high-risk OSA patients who are more prone to hypoxia during sedated endoscopy. Our team's preliminary clinical research found that High-Flow Nasal Cannula (HFNC) may reduce hypoxemia risk, but there are limited dedicated studies focusing specifically on high-risk OSA patients, with controversial results. This study aims to investigate whether HFNC can reduce the incidence of hypoxia during sedated gastrointestinal endoscopy in high-risk obstructive sleep apnea patients.

Conditions

• Hypoxemia
• Esophageal Cancer
• Gastric Cancer (Diagnosis)
• Colon Cancer

Interventions

Type	Name	Description
DEVICE	High-flow nasal cannula	Using high-flow nasal cannula oxygenation

Timeline

• Start date: 2025-09-05
• Primary completion: 2025-11-11
• Completion: 2025-11-11
• First posted: 2025-09-04
• Last updated: 2025-11-25

Locations

1 site across 1 country: China