Trials / Recruiting
RecruitingNCT07154615
Assessing Immune Dysfunction in Sepsis
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 150 (estimated)
- Sponsor
- University of Minnesota · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
Sepsis leads to sustained immune system dysfunction resulting in increased susceptibility to secondary infection while in the hospital or after discharge. Consequently, many of the \~2 million Americans that develop sepsis every year will end up back in the ICU, weeks and months later. The objective of this study is to define the cellular and molecular mechanisms driving the dysfunction and reprogramming of T cells and B cells that mediate cellular and humoral immunity using a combination of phenotypic, functional, genomic, and metabolomic assays.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Observational Only | No intervention is included in this study |
Timeline
- Start date
- 2026-03-01
- Primary completion
- 2028-11-01
- Completion
- 2028-11-01
- First posted
- 2025-09-04
- Last updated
- 2026-03-19
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT07154615. Inclusion in this directory is not an endorsement.