NCT07151287

Diagnosis of Intracranial Hypertension Using TCCD, ONSD and ODH by Bedside Ultrasound

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 64 (estimated)
• Sponsor: Xiangya Hospital of Central South University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this observational study is to investigate several means of measuring intracranial pressure (ICP) non-invasively in patients who had head trauma and received implantation of invasive ICP monitor device. The main questions it aims to answer are: What are the diagnostic efficacies of Transcranial Color-Coded Doppler Ultrasound (TCCD), Optic Nerve Sheath Diameter (ONSD) and Optic Disc Height (ODH) (the 3 non-invasive way of measuring ICP) compared with invasive ICP monitor? Participants will receive simultaneous non-invasive measurements of TCCD, ONSD and ODH along with during the days of invasive ICP monitoring. The data will be compared among the techniques to study the diagnostic efficacy.

Conditions

• Traumatic Brain Injury

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	TCCD	Patients receive non-invasive assessments of TCCD using bedside ultrasound.
DIAGNOSTIC_TEST	ONSD	Patients receive non-invasive assessments of ONSD using bedside ultrasound.
DIAGNOSTIC_TEST	ODH	Patients receive non-invasive assessments of ODH using bedside ultrasound.
DIAGNOSTIC_TEST	Invasive ICP	Patients receive invasive assessments of ICP.

Timeline

• Start date: 2025-09-15
• Primary completion: 2027-07-01
• Completion: 2027-07-01
• First posted: 2025-09-03
• Last updated: 2025-09-03