NCT07122934

Posterior Circulation Clot Burden Score (Pc-CBS) Predicts Clinical Outcome After Acute Ischemic Stroke Related to Posterior Circulation Occlusions : An Externally Validated Radiological Score

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,828 (actual)
• Sponsor: Centre Hospitalier Universitaire Vaudois · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Posterior circulation strokes (PCS) represent \~30% of all ischemic strokes, but existing prognostic tools are limited, especially for non-basilar artery occlusions. Accurate early outcome prediction may aid treatment decisions and clinical trial design. We developed and externally validated the Posterior Circulation Clot Burden Score (PC-CBS), a radiological tool to predict 3-month functional outcome in acute ischemic stroke due to posterior circulation occlusion.

Conditions

• Acute Ischemic Stroke
• Posterior Circulation Brain Infarction
• Arterial Occlusion Disease

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Assessment of cervico-cerebral arterial occlusion pattern	Assessment of cervico-cerebral arterial occlusion pattern for the development of a radiological score

Timeline

• Start date: 2003-02-01
• Primary completion: 2023-03-31
• Completion: 2025-08-08
• First posted: 2025-08-14
• Last updated: 2025-08-14