NCT07090161

Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension

• Status: Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 240 (estimated)
• Sponsor: Vanda Pharmaceuticals · Industry
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Iloperidone for the Treatment of Participants with Uncontrolled Hypertension

Conditions

• Hypertension
• Uncontrolled Hypertension

Interventions

Type	Name	Description
DRUG	iloperidone	iloperidone
DRUG	Placebo	placebo comparator

Timeline

• Start date: 2025-09-15
• Primary completion: 2026-10-01
• Completion: 2026-11-01
• First posted: 2025-07-29
• Last updated: 2026-02-27

Locations

28 sites across 1 country: United States

Regulatory

• FDA-regulated drug study