NCT07081620

Percutaneous Intercostal Cryoneuromodulation Onset Timing.

How Long Does it Take for Percutaneous Intercostal Cryoneuromodulation to Produce Cryoanalgesia? A Prospective Observational Study.

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 20 (estimated)
• Sponsor: Papa Giovanni XXIII Hospital · Academic / Other
• Sex: All
• Age: 12 Years – 40 Years
• Healthy volunteers: Accepted

Summary

Percutaneous Intercostal Cryoneurolysis is a promising technique that addresses acute postoperative pain after Nuss procedure for pectus excavatum. However its onset timing has not yet been determined. A physical examination would assess the variation of chest skin sensitivity to soft touch, cold (water at 4°C), and heat (water at 40°C) through days following the cryoneurolysis procedure.

Conditions

• Cryotherapy Effect
• Pectus Excavatum

Interventions

Type	Name	Description
OTHER	Physical examination of chest skin	soft touch and thermal (cold and warm) examination

Timeline

• Start date: 2025-06-07
• Primary completion: 2026-09-01
• Completion: 2026-11-01
• First posted: 2025-07-23
• Last updated: 2025-07-23

Locations

1 site across 1 country: Italy