NCT07080983

Efficacy of Corneal Cross-Linking (CXL) in the Treatment of Pediatric Keratoconus

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Al-Azhar University · Academic / Other
• Sex: All
• Age: 10 Years – 20 Years
• Healthy volunteers: Not accepted

Summary

This prospective interventional study investigates the efficacy of corneal cross-linking (CXL) in managing progressive keratoconus in pediatric patients. The procedure involved standard epithelium-off CXL, and patients were followed to assess outcomes such as visual acuity, keratometric stability, and corneal thickness.

Conditions

• Keratoconus

Interventions

Type	Name	Description
PROCEDURE	Crosslinking	Corneal Cross-Linking (CXL) is a minimally invasive procedure used to strengthen the cornea by increasing the chemical bonds between collagen fibers. It is primarily used to treat keratoconus and corneal ectasia, conditions where the cornea becomes progressively thinner and weaker.

Timeline

• Start date: 2024-04-02
• Primary completion: 2025-05-02
• Completion: 2025-07-01
• First posted: 2025-07-23
• Last updated: 2025-07-23

Locations

2 sites across 1 country: Egypt