NCT07074392

Assessing Spinal Accessory Nerve Recovery After Post-operative Electrical Stimulation

Assessing the Feasibility and Effect of Post-operative Electrical Stimulation on Spinal Accessory Nerve Recovery After Neck Dissection for Head and Neck Cancer

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 38 (estimated)
• Sponsor: McMaster University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Shoulder weakness and pain are common after neck dissection surgery for head and neck cancer. This is often caused by injury to the spinal accessory nerve, which controls important shoulder muscles. Recovery can be slow and incomplete, affecting patients' ability to return to daily activities. This project will test whether a brief, low-dose electrical stimulation treatment can help the nerve heal faster and improve shoulder function. The treatment is applied during surgery and is safe, non-invasive, and quick to deliver. If successful, this approach could lead to better rehabilitation, less disability, and improved quality of life for patients undergoing cancer surgery. The project also supports the development of new medical technology and offers a pathway to expand the use of electrical stimulation in other nerve injuries.

Conditions

• Head and Neck Cancer
• Nerve Injury
• Neck Dissection

Interventions

Type	Name	Description
DEVICE	Electrical Stimulation	Custom stimulator will deliver a 1hour stimulation protocol post-operatively at 20 Hz, with biphasic pulses (100 µs duration, 0-2mA amplitude range).

Timeline

• Start date: 2026-01-01
• Primary completion: 2027-01-01
• Completion: 2027-03-01
• First posted: 2025-07-20
• Last updated: 2025-08-19

Locations

1 site across 1 country: Canada