NCT07024264

Measured Versus Estimated Energy Requirement in the ICU Patients

Caloric Estimation Using Predictive Equations and Indirect Calorimetry in ICU Patients

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 133 (actual)
• Sponsor: Taipei Medical University Shuang Ho Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 105 Years
• Healthy volunteers: Not accepted

Summary

The goal of this observational study is to compare energy requirements estimated by predictive equation and indirect calorimetry across different BMI categories, and to examine how these estimates, along with early nutritional strategies and progressive caloric delivery relate to ICU outcomes. The main questions it aims to answer are: 1. To evaluate whether predictive equation and/or indirect calorimetry provides accurate caloric targets in critically ill patients. 2. To identify high-risk malnutrition patients (underweight, normal and overweight, obese) who may benefit most from IC-based measurement. 3. To investigate the impact of caloric strategies and nutritional achievement during the acute phase on the length of ICU stay.

Conditions

• Critical Illness
• Energy Requirement
• Equation
• Indirect Calorimetry
• Malnutrition

Interventions

Type	Name	Description
OTHER	Total energy requirement calculated by predictive equation	Critically ill patients are highly susceptible to malnutrition, making accurate caloric estimation essential to prevent both underfeeding and overfeeding during the acute phase in the ICU. Although predictive equations (PE) are widely used to estimate energy requirement, indirect calorimetry (IC) remains the gold standard. This study aimed to compare energy requirements estimated by PE and IC across different BMI categories.

Timeline

• Start date: 2022-10-01
• Primary completion: 2024-03-31
• Completion: 2024-03-31
• First posted: 2025-06-17
• Last updated: 2025-06-17

Locations

1 site across 1 country: Taiwan