NCT07022730

Prophylactic Noradrenaline Infusion and Its Impact on Post-induction Hypotension

The Novel Use of Prophylactic Noradrenaline Infusion and Its Impact on Post-induction Hypotension in Patients With Surgical Sepsis, a Double Blind Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 20 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

researchers aim to evaluate the influence of prophylactic noradrenaline infusion on post-induction hypotension

Detailed description

If post-induction hypotension is not addressed promptly, it can lead to severe complications such as reduced blood flow, acute kidney damage, and myocardial ischemia. As a result, early detection and proactive intervention are crucial. Researchers of the current study decided to investigate impact of noradrenaline administered as a prophylaxis on post induction hypotension

Conditions

• Post Induction Hypotension
• Sepsis

Interventions

Type	Name	Description
DRUG	Noradrenaline 0.2 mcg/kg/min at 5 minutes before induction	noradrenaline will be given at a rate of 0.2 mcg/kg/min that will start 5 minutes before induction

Timeline

• Start date: 2025-06-22
• Primary completion: 2025-09-17
• Completion: 2025-09-17
• First posted: 2025-06-15
• Last updated: 2025-09-18

Locations

1 site across 1 country: Egypt