NCT07022041

Sepsis and Hospital Mortality

Sepsis Mortality in Hospitals: a Quality Indicator in Acute Care Settings

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: University of Calabria · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Sepsis is one of the leading causes of hospital mortality, with a rate of approximately 20% (World Health Organization) among vulnerable patients admitted to high-intensity care units such as CCUs and inpatient wards. Currently, diagnostic criteria such as the Systemic Inflammatory Response Syndrome (SIRS) and the Sequential Organ Failure Assessment (SOFA) score, although widely used, lack sufficient specificity and accuracy. No established parameters are available for early and timely diagnosis. This study aims to address this gap by investigating the variability of blood plasma conductivity and dielectric constant using microwave probes previously validated for non-invasive glucose monitoring. The acquired data will be analyzed using the Anritsu VectorStar VNA to identify innovative and reliable parameters associated with the presence of severe infections.

Conditions

• Sepsis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	conductivity and dieletric constant	collecting blood samples and directly measuring plasma conductivity and dielectric constant using microwave probes already validated for non-invasive glucose monitoring.

Timeline

• Start date: 2025-07-15
• Primary completion: 2026-07-15
• Completion: 2026-12-15
• First posted: 2025-06-15
• Last updated: 2025-08-07

Locations

1 site across 1 country: Italy