NCT07006545

Return to Activity After Total Knee Arthroplasty

Prospective, Multicenter Study of Clinical Rehabilitation and Return-to-activity After Total Knee Arthroplasty

• Status: Enrolling By Invitation
• Phase: —
• Study type: Observational
• Enrollment: 400 (estimated)
• Sponsor: University Hospital, Bonn · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This multicenter research project aims to correlate objective testing of muscle mass, muscle strength, neuromuscular activation, walking speed and other functional tests with everyday activity and subjective quality of life after total knee arthroplasty. For this purpose, 400 patients from 5 orthopedic departments in Germany and USA will be examined at the time points pre-op, six weeks, three, six and 12 months post-op.

Conditions

• Total Knee Arthroplasty

Interventions

Type	Name	Description
OTHER	Return to Activity Battery	The main target parameters are muscle mass (sonography), muscle strength (isometric maximum strength measurement), neuromuscular activation (surface EMG), functionality (e.g. 6MWT, chair rising test), knee swelling and subjective assessment of everyday and leisure activities, quality of life (e.g. SF-36) and return to work

Timeline

• Start date: 2024-04-01
• Primary completion: 2026-12-31
• Completion: 2027-07-31
• First posted: 2025-06-05
• Last updated: 2025-06-05

Locations

2 sites across 1 country: Germany